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novel coronavirus (2019-nCoV) 病毒:新型冠状病毒 2019-nCoV

COVID‑19 Information & Resources

COVID‑19 Information & Resources

COVID‑19 Information & Resources

image162

 

Coronavirus disease (COVID‑19)

Also called: 2019-nCov, 2019 Novel Coronavirus

OVERVIEW

SYMPTOMS

PREVENTION

TREATMENTS 


 

Coronavirus symptoms: What are they and how do I protect myself?

By James GallagherHealth and science correspondent 30 March 2020

 https://www.bbc.com/news/health-51048366 

 

Tracking Covid-19 cases in the US

Since January, novel coronavirus has spread to nearly every state and territory

By Sergio Hernandez, Sean O’Key, Amanda Watts, Byron Manley and Henrik Pettersson, CNN

Last updated: March 30, 2020 at 8:00 p.m. ET

 https://www.cnn.com/interactive/2020/health/coronavirus-us-maps-and-cases/ 


 This map is your interactive guide to confirmed cases, recoveries and deaths from the coronavirus around the state, nation and world. It combines data from the World Health Organization, U.S. and European CDCs, and the National Health Commission of China. 

 https://data.courierpostonline.com/coronavirus/ 


 The COVID Tracking Project

 https://covidtracking.com/data/ 


 https://coronavirus.1point3acres.com/en 


 https://www.bing.com/covid 

 

Coronavirus Live Updates: Despite Pushback, Trump Suggests Testing No Longer an Issue

Maryland and Virginia issued statewide stay-at-home orders, and the F.D.A. approved two malaria drugs to treat coronavirus patients. Macy’s said it would furlough most of its 125,000 workers.

RIGHT NOW

President Trump said the United States soon will be producing so many ventilators and other medical equipment that the government will be sending supplies to hard-hit Europe.

新冠病毒疫情最新消息

 https://www.nytimes.com/2020/03/30/world/coronavirus-live-news-updates.html 


 

Coronavirus Live Updates: U.S. Leads the World in Known Cases

 https://www.nytimes.com/2020/03/26/world/coronavirus-news.html  

Coronavirus in the U.S.: Latest Map and Case Count

By Mitch Smith, Karen Yourish, Sarah Almukhtar, Keith Collins, Danielle Ivory, Allison McCann, Jin Wu and Amy HarmonUpdated March 26, 2020, 5:27 P.M. E.T.

Map 

 https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html 



 Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU)
https://coronavirus.jhu.edu/map.html 


 Mar 27, 2020 04:02 AMSOCIETY & CULTURE

Keys in Fighting Covid-19 Are Testing, Tracing, Isolation, WHO Says

By Tian Jiawei, Zeng Jia and Han Wei 

 https://www.caixinglobal.com/2020-03-27/keys-in-fighting-covid-19-are-testing-tracing-isolation-who-says-101534587.html 




 

Coronavirus symptoms: A list and when to seek help

By Sandee LaMotte, CNN

Updated 11:00 AM ET, Fri March 20, 2020

 https://www.cnn.com/2020/03/20/health/coronavirus-symptoms-list-what-to-do-wellness/index.html 


 Mar 23, 2020 09:32 PM

Despite Official Figures, Wuhan Continues to Find New Asymptomatic Covid-19 Cases Daily

By Zhao Jinzhao and Dave Yin 

 https://www.caixinglobal.com/2020-03-23/despite-official-figures-wuhan-continues-to-find-new-asymptomatic-covid-19-cases-daily-101532880.html 


 Mar 23, 2020 09:46 PMSOCIETY & CULTURE

Coronavirus Live Updates (Monday): China’s Ambassador to U.S. Criticizes Coronavirus Conspiracy Theories

 https://www.caixinglobal.com/2020-03-23/coronavirus-live-updates-monday-hong-kong-reports-more-new-cases-than-chinese-mainland-global-infections-top-330000-101532621.html 

 

Hong Kong appeared to have the coronavirus under control, then it let its guard down

Analysis by James Griffiths, CNN

Updated 4:37 AM ET, Mon March 23, 2020

 https://www.cnn.com/2020/03/23/asia/hong-kong-coronavirus-quarantine-intl-hnk/index.html


 

New York launches use of malaria drug to treat Covid-19

Mar. 23, 2020 1:26 PM ET|About: Tekla World Healthcare... (THW)|By: , SA News Editor  

 https://seekingalpha.com/news/3554308-new-york-launches-use-of-malaria-drug-to-treat-covidminus-19  


New York governor: "We haven't flattened the curve ... the curve is actually increasing"

 

Coronavirus pandemic changes life as we know it

By Jessie Yeung, Helen Regan, Adam Renton, Emma Reynolds, Mike Hayes and Meg Wagner, CNN

Updated 1:10 p.m. ET, March 24, 2020 

 https://www.cnn.com/world/live-news/coronavirus-outbreak-03-24-20-intl-hnk/h_478a57ca8ce9ac53c3b9816327f7d0f8 

 

Cuomo Says Virus Cases Increasing Rapidly Despite Lockdown

By March 24, 2020, 11:16 AM EDT Updated on March 24, 2020, 11:41 AM EDT

  • New York has 10 times more cases than California, Cuomo says
  • Lack of ventilators seen as a huge problem once N.Y. hits apex

 https://www.bloomberg.com/news/articles/2020-03-24/n-y-s-cuomo-says-rate-of-virus-cases-increasing-despite-actions?srnd=premium 


 Mar 25, 2020 07:18 PM

High Elderly Population, Limited Testing May Underlie Italy’s High Covid-19 Death Rate: Paper

By Zeng Yukun, Ma Danmeng and Yang Ge 

 https://www.caixinglobal.com/2020-03-25/high-elderly-population-limited-testing-may-underlie-italys-high-covid-19-death-rate-paper-101533943.html 


 The George Washington University Hospital  

Important Coronavirus Update

Coronavirus Disease 2019, or COVID-19

 https://www.gwhospital.com/health-alert 

 

Coronavirus: loss of smell or taste could be a symptom, growing evidence suggests

  • Studies and observations in several countries indicate significant numbers of patients experience a loss of smell
  • Identifying these symptoms could allow testing and isolation of people who would otherwise infect others, doctors say

Sarah Zheng

Published: 4:58pm, 25 Mar, 2020

 https://www.scmp.com/news/china/society/article/3076933/coronavirus-loss-smell-or-taste-could-be-symptom-growing 


 Mar 27, 2020 09:24 PMSOCIETY & CULTURE

New Study Indicates Coronavirus Spreads Easily Even When Symptoms Are Mild

By Wen Simin and Timmy Shen 

 https://www.caixinglobal.com/2020-03-27/new-study-indicates-coronavirus-spreads-easily-even-when-symptoms-are-mild-101535113.html 

 

Under Intense Criticism, Trump Says Government Will Buy More Ventilators

In another day of mixed messages, the president criticized G.M. and authorized the use of the Defense Production Act to force it to make ventilators after the company had already announced it was going to.

By David E. Sanger, Maggie Haberman and Annie Karni  March 27, 2020

 https://www.nytimes.com/2020/03/27/us/politics/coronavirus-trump-ventilators-gm-ventec.html 

 

Coronavirus Live Updates: Pelosi Accuses Trump of ‘Deadly’ Denial and Governors Plead for Help; New York Mayor Says Medical Supplies Will Run Out in a Week

 https://www.nytimes.com/2020/03/29/world/coronavirus-news.html 


Coronavirus: China ramps up Covid-19 test kit exports amid global shortage, as domestic demand dries up

  • More than 100 Chinese companies are selling coronavirus testing kits to Europe, but most are not licensed to sell in China
  • A global shortage of kits has sparked a scramble for resources, but the specialist nature of the production process provides limitations

Finbarr Bermingham, Sidney Leng and Echo Xie in Beijing

Published: 6:00am, 30 Mar, 2020

 https://www.scmp.com/economy/china-economy/article/3077314/coronavirus-china-ramps-covid-19-test-kit-exports-amid-global 



Biotech-War$ Burn The Ships

COVID‑19 Information & Resources

COVID‑19 Information & Resources

image163

 

Biotech-War$ Burn The Ships

Mar. 27, 2020 3:47 PM ET|About: Gilead Sciences, Inc. (GILD), Includes: JNJ, MRNA, RHHBY, VIR

Summary


Politicos from every country have failed to understand and to effectively battle the Covid-19 virus.


Politicos from every country have failed to understand and to effectively battle the Covid-19 virus.


The virus was the pin the popped the highly leveraged and overconfident market that many were indicating/predicting needed some adjustment. But not many were forecasting a -37% “pin” reduction vs.Jan.


an antiviral drug is a virus suppressant that blocks the chemical compounds that the virus needs for replication, its goal is to reduce the number of virus counts in the body to a manageable state.

 

Biotech-War$ Burn The Ships

Mar. 27, 2020 3:47 PM ET|About: Gilead Sciences, Inc. (GILD), Includes: JNJ, MRNA, RHHBY, VIR 


 https://seekingalpha.com/instablog/5205071-danwatson888/5426472-biotech-war-burn-ships 


 https://seekingbiotechalpha.com/biotechstorm 





 

History's verdict on Trump will be devastating

By Michael D'Antonio

Updated 6:14 PM ET, Mon March 30, 2020

 https://www.cnn.com/2020/03/30/opinions/history-verdict-on-trump-devastating-dantonio/index.html 

 

Trauma physician treating coronavirus patients worries ''we are slowly descending into chaos'

By Holly Yan, Madeline Holcombe and Steve Almasy, CNN

Updated 7:52 PM ET, Mon March 30, 2020

 https://www.cnn.com/2020/03/30/health/us-coronavirus-updates-monday/index.html 

 

Nurses Die, Doctors Fall Sick and Panic Rises on Virus Front Lines

The pandemic has begun to sweep through New York City’s medical ranks, and anxiety is growing among normally dispassionate medical professionals.

By Michael Schwirtz

  • March 30, 2020, 5:00 a.m. ET

 https://www.nytimes.com/2020/03/30/nyregion/ny-coronavirus-doctors-sick.html 

 

Shielding the Fetus From the Coronavirus

New studies suggest the virus can cross the placenta, but newborns have been mildly affected if at all.

By Apoorva Mandavilli  March 27, 2020

 https://www.nytimes.com/2020/03/27/health/shielding-the-fetus-from-the-coronavirus.html 

 

Some U.S. Cities Could Have Coronavirus Outbreaks Worse Than Wuhan’s

By Nate Cohn, Josh Katz, Margot Sanger-Katz and Kevin QuealyMarch 27, 2020

 https://www.nytimes.com/interactive/2020/03/27/upshot/coronavirus-new-york-comparison.html 


What it's like for health care workers on the front lines of the coronavirus pandemic

By Dakin Andone, CNN

Updated 8:04 PM ET, Sat March 28, 2020

 https://www.cnn.com/2020/03/27/us/inside-hospitals-coronavirus-vignettes/index.html 

 

Coronavirus death toll in the US passes 2,000 as Trump says New York quarantine 'will not be necessary'

By Dakin Andone and Christina Maxouris, CNN

Updated 9:28 PM ET, Sat March 28, 2020

 https://www.cnn.com/2020/03/28/health/us-coronavirus-weekend-saturday/index.html 

 

America squandered its best chance of containing the virus because of faulty test kits, red tape and lapses in leadership, interviews show.

By Michael D. Shear, Abby Goodnough, Sheila Kaplan, Sheri Fink, Katie Thomas and Noah Weiland   March 28, 2020

 https://www.nytimes.com/2020/03/28/us/testing-coronavirus-pandemic.html 


 

N.Y.C.’s 911 System Is Overwhelmed. ‘I’m Terrified,’ a Paramedic Says.

With coronavirus cases mounting, emergency workers are making life-or-death decisions about who goes to a hospital, and who is left behind.

By Ali Watkins  March 28, 2020

 https://www.nytimes.com/2020/03/28/nyregion/nyc-coronavirus-ems.html 

 

Coronavirus in the U.S.: Latest Map and Case Count

By Mitch Smith, Karen Yourish, Sarah Almukhtar, Keith Collins, Danielle Ivory, Allison McCann, Jin Wu and Amy HarmonUpdated March 29, 2020, 8:02 A.M. E.T.

 https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html 

 

Opinion

Let’s ‘Kick Coronavirus’s Ass’

In this nightmarish moment, we’re feeling warm and fuzzy about the cold and calculating Andrew Cuomo. 

By Maureen Dowd  Opinion Columnist

March 27, 2020

 https://www.nytimes.com/2020/03/27/opinion/sunday/cuomo-new-york-coronavirus.html 


 Mar 29, 2020 12:47 PMSOCIETY & CULTURE

Zhejiang Covid-19 Infection Highlights Threat from Asymptomatic Carriers

By Zhang Erchi and Guo Yingzhe 

 https://www.caixinglobal.com/2020-03-29/zhejiang-covid-19-infection-highlights-threat-from-asymptomatic-carriers-101535677.html 

 

New Chinese research may point to possible role of children in coronavirus spread

  • Covid-19 symptoms tend to be milder in kids, according to studies in Zhejiang and Wuhan, with asymptomatic infections ‘not uncommon’
  • But health experts say more investigation into the chain of transmission is needed

Matt Ho and Jane Cai

Published: 10:00am, 29 Mar, 2020

 https://www.scmp.com/news/china/society/article/3077402/new-chinese-research-may-point-possible-role-children 

 

Coronavirus: China can’t suppress it, US military can’t kill it. Covid-19 is the real Godzilla

  • The truth to emerge from the pandemic is that all humans share a common destiny, and we are embroiled in our biggest battle since World War II
  • Only when the human race chooses to share, help, care, cooperate and support each other can we beat this enemy from nature

Cary Huang

Published: 11:30am, 29 Mar, 2020

 https://www.scmp.com/week-asia/opinion/article/3077321/coronavirus-china-cant-suppress-it-us-military-cant-kill-it-covid 

 

Decoding Covid-19

Seven human coronaviruses in seven graphics

 https://multimedia.scmp.com/infographics/news/china/article/3075382/decoding-coronavirus-covid-19/index.html?src=article-launcher 


 Mar 29, 2020 06:41 PMOPINION

As U.S. Sits on Ample Ventilator Supply, China Wages Must-Win Battle to Contain Covid-19 in Hubei

By Wang Shuo 

 https://www.caixinglobal.com/2020-03-29/as-us-sits-on-ample-ventilator-supply-china-wages-must-win-battle-to-contain-covid-19-in-hubei-101535747.html 

 

US could see millions of coronavirus cases and 100,000 or more deaths, Fauci says

By Devan Cole, CNN

Updated 1:27 PM ET, Sun March 29, 2020

 https://www.cnn.com/2020/03/29/politics/coronavirus-deaths-cases-anthony-fauci-cnntv/index.html 

 

Coronavirus: social distancing could save millions of lives, study says

  • Researchers from Imperial College in London say that without steps such as social distancing Covid-19 could have killed 40 million people this year
  • Study warns governments will have to make ‘challenging decisions’ but limiting social contacts could halve the death toll

Matt Ho

Published: 7:00am, 31 Mar, 2020

 https://www.scmp.com/news/china/society/article/3077646/coronavirus-social-distancing-could-save-millions-lives-study 


 

Doctors on frontline of China’s battle with coronavirus tell of race to respond to onset of new disease

  • One doctor in Wuhan describes the emotional toll of trying to care for Covid-19 patients and warns that the most serious cases are still struggling to make it
  • Medical staff had to learn on the job when treating the previously unknown disease, which may have cost some patients their lives

Zhuang Pinghui in Beijing

Published: 7:00am, 1 Apr, 2020

 https://www.scmp.com/news/china/society/article/3077796/doctors-frontline-battle-coronavirus-tell-race-respond-onset-new 






Remdesivir (GS-5734)

COVID‑19 Information & Resources

the FDA has exercised “enforcement discretion” with respect to LDTs.

image164

   remdesivir 

 

Gilead Expands Emergency Access to Experimental Coronavirus Drug

By March 28, 2020, 6:21 PM EDT Updated on March 29, 2020, 4:49 AM EDT

  • Remdesivir given to over 1,000 patients for compassionate use
  • Multiple clinical trials may report initial results in weeks

 https://www.bloomberg.com/news/articles/2020-03-28/gilead-says-it-s-expanding-access-to-covid-19-drug?utm_campaign=news&utm_medium=bd&utm_source=applenews 


 01-Apr-2020

GILEAD SCIENCES ANNOUNCES TWO PHASE 3 RANDOMISED STUDIES TO EVALUATE THE SAFETY AND ANTIVIRAL ACTIVITY OF REMDESIVIR (GS-5734™) IN PARTICIPANTS WITH MODERATE TO SEVERE COVID-19

  • Remdesivir is an investigational agent – it is not approved anywhere globally and has not been demonstrated to be safe or effective for any use.
  • The UK is one of the countries where Gilead is running clinical trials to evaluate remdesivir for the treatment of COVID-19

London, April 1st 2020 – Gilead Sciences 

 https://www.pharmiweb.com/press-release/2020-04-01/gilead-sciences-announces-two-phase-3-randomised-studies-to-evaluate-the-safety-and-antiviral-activity-of-remdesivir-gs-5734-in-participants-with-m 


 Gilead Sciences Statement on Request to Rescind Remdesivir Orphan Drug Designation 

 https://www.gilead.com/-/media/gilead-corporate/files/pdfs/company-statements/remdesivir-orphan-drug-designation.pdf?la=en&hash=ED14BC7B26E2FEAA2E31E7741A8C9692 

 

Gilead CEO: We're on track to have initial data in the coming weeks

Mar. 28, 2020 6:19 PM ET|About: Gilead Sciences, Inc. (GILD)|By: , SA News Editor  

 https://seekingalpha.com/news/3556087-gilead-ceo-on-track-to-initial-data-in-coming-weeks 

 

An Open Letter from our Chairman and CEO

Daniel O’Day - March 28, 2020

 https://www.gilead.com/stories/articles/an-open-letter-from-our-chairman-and-ceo 



Three coronavirus patients in Taiwan see fevers subside after taking remdesivir

Remdesivir in clinical trials to assess effectiveness in treating COVID-19

  9636   

By George Liao, Taiwan News, Staff Writer

2020/03/26 21:24

 https://www.taiwannews.com.tw/en/news/3905171 

 

Gilead to withdraw Orphan Drug tag for remdesivir;

 Mar. 25, 2020 1:24 PM ET|About: Gilead Sciences, Inc. (GILD)|By: , SA News Editor 

 https://seekingalpha.com/news/3555135-gilead-to-withdraw-orphan-drug-tag-for-remdesivir-shares-down-3 

 

Covid Report: Gilead Asks FDA To Rescind Key Status For Coronavirus Drug

 04:15 PM ET 03/25/2020

 https://www.investors.com/news/technology/coronavirus-treatment-gild-stock-dives-asks-fda-rescind-key-status-covid-19-drug/?refcode=TechReport-03252020-3-DA-1:03:2020:1Q:NewsLetter:Email:TechReport-03252020:na:na:na:na:25:14:3:DA:1 

 

Gilead's Remdesivir receives orphan drug status for coronavirus

Mar. 23, 2020 4:34 PM ET|About: Gilead Sciences, Inc. (GILD)|By: , SA News Editor  

 https://seekingalpha.com/news/3554448-gileads-remdesivir-receives-orphan-drug-status-for-coronavirus 

 

Gilead Sciences Update On The Company’s Ongoing Response To COVID-19

 https://www.gilead.com/purpose/advancing-global-health/covid-19 

 

 https://seekingalpha.com/symbol/GILD 


 Gilead Mulls Hiring Remdesivir OEMs in China if Drug Passes Clinical TrialsTANG SHIHUADATE : MAR 25 2020/SOURCE : YICAI 

 https://yicaiglobal.com/news/gilead-mulls-hiring-remdesivir-oems-in-china-if-drug-passes-clinical-trials 

 

Coronavirus Patients in Limbo as Gilead Suspends Emergency Drug Access

The company says it will switch to a broader approach for its experimental drug, remdesivir. But it was overwhelmed by demand for a potential treatment promoted by President Trump.

 By Katie Thomas March 23, 2020

 https://www.nytimes.com/2020/03/23/health/coronavirus-drugs-remdesivir.html 


 CORONAVIRUS

Coronavirus treatment: Palo Alto woman recovers from coronavirus after being treated with remdesivir

 By

Wednesday, March 25, 2020 8:50PM

PALO ALTO, Calif. (KGO) 

 https://abc7news.com/6047442/ 



 

The race is on in the drug battle against the coronavirus

  • Researchers are looking to repurpose existing pharmaceuticals to target a disease that has already killed thousands around the world
  • Some have potential in helping those at greatest risk, virologist says

Josephine Ma

Published: 8:00am, 24 Mar, 2020

 https://www.scmp.com/news/china/society/article/3076502/race-drug-battle-against-coronavirus 

 

Coronavirus in NJ: Going to 'get worse before it gets better' says hospital chief

, Asbury Park PressPublished 5:00 a.m. ET March 24, 2020 | Updated 7:44 a.m. ET March 24, 2020 

 https://www.app.com/story/news/health/2020/03/24/coronavirus-nj-going-get-worse-before-gets-better-says-hospital-chief/2901766001 


 

Coronavirus updates: U.S. could become new coronavirus epicenter, WHO says

UPDATED ON: MARCH 24, 2020 / 2:29 PM / CBS NEWS

 https://www.cbsnews.com/live-updates/coronavirus-disease-covid-19-latest-news-deaths-2020-03-24/ 


 

Coronavirus patients may be most infectious in first week of symptoms, study finds

  • Researchers find viral load highest in first seven days after patients start showing signs of the disease
  • Self-collected saliva samples could be safer than throat and nasal swabs taken by medical professionals, they say

Mandy Zuo in Shanghai and Holly Chik

Published: 8:30pm, 25 Mar, 2020

 https://www.scmp.com/news/china/society/article/3076959/coronavirus-patients-may-be-most-infectious-first-week-symptoms 


 Opinion  

Dale Fisher

Why Singapore’s coronavirus response worked – and what we can all learn

  • It’s really about leadership being organised enough to get the messaging right. People will feel more comfortable and are more likely to follow the rules
  • In Singapore, we want life to go on as normal. We want businesses, churches, restaurants and schools to stay open. This is what success looks like

Dale Fisher

Published: 12:42pm, 25 Mar, 2020

 https://www.scmp.com/week-asia/opinion/article/3076885/why-singapores-coronavirus-response-worked-and-what-we-can-all 


 

WHO chooses Malaysia to run trials on new drug to fight Covid-19

 PUBLISHED

MAR 28, 2020, 3:00 PM SGT 

 PETALING JAYA (THE STAR/ASIA NEWS NETWORK) 

 https://www.straitstimes.com/asia/se-asia/who-chooses-malaysia-to-run-trials-on-new-drug-to-fight-covid-19 



 

Funeral parlour report fans fears over Wuhan death toll from coronavirus

  • Magazine quotes truck driver saying he delivered thousands of funeral urns to facilities in the city last week
  • Relatives of deceased only able to collect ashes in last week as centres in the city began clearing backlog

 The comment came after reports that funeral homes in Wuhan have ordered thousands more urns than the official death tally of coronavirus patients in the city.

In a report on the weekend, Caixin magazine quoted a truck driver as saying he delivered about 5,000 urns on Wednesday and Thursday to the funeral parlour in Hankou district – one of eight such facilities in the city.


William Zheng

Published: 11:00pm, 30 Mar, 2020

 https://www.scmp.com/news/china/society/article/3077644/funeral-parlour-report-fans-fears-over-wuhan-death-toll 



the FDA has exercised “enforcement discretion” with respect to LDTs.

Coronavirus update U.S., Trump administration response under scrutiny

the FDA has exercised “enforcement discretion” with respect to LDTs.

 EYE ON THE NEWS

A Self-Inflicted Crisis

Overregulation has played a dangerous role in America’s coronavirus outbreak.Roger D. KleinMarch 4, 2020 Health Care 


 For those without known exposures, CDC only recommends testing for severely affected patients. In theory, doctors could have tested any individuals in whom they suspected coronavirus, and Vice President Pence on March 3rd encouraged this; however, the unavailability of testing has been a major obstacle in practice. On February 4, following Health and Human Services Secretary Alex Azar’s declaration of a public-health emergency, the Food and Drug Administration issued an Emergency Use Authorization (EUA) to the CDC, allowing it to distribute test kits to designated public-health laboratories. The CDC began shipping the kits on February 5, but laboratories could not validate them because they contained a defective reagent. 



 Prognosis

U.S. Will Miss Coronavirus Test Rollout Goal, Senators Say

By , , and March 5, 2020, 9:48 AM EST Updated on March 5, 2020, 12:10 PM EST

  • GOP senators says kits to be in mail by end of this week
  • Distribution, training ‘going to take time,’ Lankford says

 https://www.bloomberg.com/news/articles/2020-03-05/u-s-won-t-meet-coronavirus-test-rollout-goal-senators-say 


 Mar 07, 2020 08:25 AMSOCIETY & CULTURE

Covid-19 Relapse Mystery May Be Linked to Controversial Treatment, Researchers Say

By Zhang Yang, Huang Shulun and Denise Jia 

 https://www.caixinglobal.com/2020-03-07/covid-19-relapse-mystery-may-be-linked-to-controversial-treatment-researchers-say-101525073.html 


 

Facts about novel coronavirus and how to prevent COVID-19

March 6, 2020 at 7:19 am Updated March 7, 2020 at 11:08 am 

 By 

 

Seattle Times graphics editor

 https://www.seattletimes.com/seattle-news/health/facts-about-novel-coronavirus-and-how-to-prevent-covid-19/ 


 Prognosis

Virus Testing Blitz Appears to Keep Korea Death Rate Low

By , , and March 4, 2020, 4:00 PM EST Updated on March 5, 2020, 1:18 AM EST

  • Country is testing at fastest global pace as cases top 5,000
  • Faulty, limited testing in Japan, U.S., could worsen outbreak

 

 https://www.bloomberg.com/news/articles/2020-03-04/south-korea-tests-hundreds-of-thousands-to-fight-virus-outbreak 

 

CORONAVIRUS

How South Korea Scaled Coronavirus Testing While the U.S. Fell Dangerously Behind

By learning from a MERS outbreak in 2015, South Korea was prepared and acted swiftly to ramp up testing when the new coronavirus appeared there. Meanwhile, the U.S., plagued by delay and dysfunction, wasted its advantage.

by Stephen Engelberg, Lisa Song and Lydia DePillis

March 15, 11:10 a.m. EDT 

 https://www.propublica.org/article/how-south-korea-scaled-coronavirus-testing-while-the-us-fell-dangerously-behind 


 

WATCH: FDA Seeks To Expand Treatment Options For Coronavirus

March 19, 20209:26 AM ET

TwitterInstagram 

 https://www.npr.org/2020/03/19/817971577/trump-governors-to-discuss-coronavirus-strategy-as-fema-takes-bigger-role 


 

Coronavirus: Grim toll as Italy’s Covid-19 deaths surpass those of China

  • Italian authorities announce 427 new deaths, pushing the total to 3,405 and exceeding mainland China’s 3,242
  • In Madrid, death rate is described by health authorities as ‘one case every 16 minutes’

Stuart Lau

Published: 12:08am, 20 Mar, 2020

 https://www.scmp.com/news/china/article/3076015/coronavirus-grim-toll-italy-number-deaths-near-chinas-total 

What Two Months of Reporting Has Taught Caixin About the Coronavirus

Coronavirus update U.S., Trump administration response under scrutiny

Coronavirus update U.S., Trump administration response under scrutiny


  Mar 16, 2020 09:15 PMSOCIETY & CULTURE

Reporter’s Notebook: What Two Months of Reporting Has Taught Caixin About the Coronavirus

By Han Wei 

 https://www.caixinglobal.com/2020-03-16/reporters-notebook-what-two-months-of-reporting-has-taught-caixin-about-the-coronavirus-101529285.html 


 

How China’s military took a frontline role in the coronavirus crisis

  • Chinese President Xi Jinping, who gave army medical teams the heaviest responsibilities, says virus is now ‘basically curbed’ thanks to their efforts
  • PLA’s Academy of Military Medical Sciences personnel have decades of experience including tackling Sars, Ebola, and the earthquake that shattered Sichuan in 2008

Minnie Chan

Published: 6:00am, 17 Mar, 2020

 https://www.scmp.com/news/china/military/article/3075396/how-chinas-military-took-frontline-role-coronavirus-crisis 


 Economy / China Economy

Coronavirus: China’s economy suffers dramatic collapse in January, February in warning to rest of world

  • Combined data for January and February showed that industrial production, retail sales and asset investment all declined far more than analysts expected
  • Lockdowns to control the coronavirus proved to be a constraint to economic growth, but with China now in recovery, data suggests what rest of the world could expect

Finbarr Bermingham and Orange Wang

Published: 10:00am, 16 Mar, 2020

 https://www.scmp.com/economy/china-economy/article/3075314/coronavirus-caused-dramatic-collapse-chinas-economy-warning 


 Mar 16, 2020 08:58 PMBUSINESS & TECH

Restaurants in China Are Reopening, But Finding It Hard to Recover Business

By Shen Xinyue and Isabelle Li 

 https://www.caixinglobal.com/2020-03-16/restaurants-in-china-are-reopening-but-finding-it-hard-to-recover-business-101529295.html 


 

COVID-19: Containing and conquering a global health threat

 https://www.roche.com/research_and_development/what_we_are_working_on/infectious_diseases/coronavirus.htm 


 The Fatal Impact of Coronavirus Lockdown 

 https://www.caixinglobal.com/2020-03-15/gallery-the-fatal-impact-of-coronavirus-lockdown-101528806.html 


 

One chart shows how the coronavirus is more deadly than the flu even in South Korea, where the COVID-19 death rate is low

Andy Kiersz Mar 12, 2020, 5:18 PM

 https://www.businessinsider.com/coronavirus-death-rate-south-korea-compared-to-flu-2020-3 


 Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents 

 https://www.journalofhospitalinfection.com/article/S0195-6701(20)30046-3/pdf 

 

The incompetence pandemic

  • The first victim of the coronavirus? Leadership

POLITICO

Published: 12:49pm, 16 Mar, 2020

 https://www.scmp.com/news/world/united-states-canada/article/3075336/incompetence-pandemic 

 This story is published in a content partnership with POLITICO. It was originally reported by Matthew Karnitschnig on 

politico.com

on March 16, 2020. 


The incompetence pandemic

The first victim of the coronavirus? Leadership.

 https://www.politico.com/news/2020/03/16/coronavirus-pandemic-leadership-131540 


 

Coronavirus: US officials overruled expert advice on listing places visited by Patient 1

  • Emails reveal that Washington state health officials ignored an earlier plan by a senior epidemiologist to name locations
  • Hong Kong, South Korea and Singapore have been credited with slowing the outbreak by disclosing details about the movements of infected patients

John Power

Published: 8:00pm, 23 Mar, 2020

 https://www.scmp.com/week-asia/health-environment/article/3076477/coronavirus-us-officials-overruled-expert-advice 




Coronavirus update U.S., Trump administration response under scrutiny

Coronavirus update U.S., Trump administration response under scrutiny

Coronavirus update U.S., Trump administration response under scrutiny


Coronavirus update: 82,550 cases, 2,810 deaths, 1 possible case of spread in the U.S., Trump administration response under scrutiny

142Published: Feb. 27, 2020 at 3:26 p.m. ETBy 

 

A woman in Northern California who tested positive for COVID-19 had not traveled to an affected country or likely been in contact with another confirmed case



 Mar 06, 2020 06:39 AMSOCIETY & CULTURE

Coronavirus Live Updates (Thursday): As Domestic Outbreak Ebbs, China Faces Waves of Cases Imported From Iran, Italy


 https://www.caixinglobal.com/2020-03-06/coronavirus-live-updates-thursday-china-reports-20-imported-cases-california-declares-emergency-101524340.html 


  Home / China / Info & tips

10 measures to help control epidemic, restart work

chinadaily.com.cn | Updated: 2020-03-05 20:37  

 http://global.chinadaily.com.cn/a/202003/05/WS5e60f294a31012821727caf7.html 

 

Coronavirus: global infections could increase tenfold every 19 days, Chinese study says

  • Nation’s leading geneticist Jin Li calls on the world to ‘take strong actions on public health, using experiences learned from China and Singapore’
  • Chilling forecast based on simple linear model, though research has yet to be peer-reviewed

Stephen Chen in Beijing

Published: 6:11pm, 7 Mar, 2020

 https://www.scmp.com/news/china/science/article/3074080/coronavirus-global-infections-could-increase-tenfold-every-19 


 Coronavirus 

SCMP

LAST UPDATED: MAR 7, 9 

Source: China's NHC, state media, other authorities

 https://multimedia.scmp.com/widgets/china/wuhanvirus/ 

 

How It All Started: China’s Early Coronavirus Missteps

China’s errors, dating back to the very first patients, were compounded by political leaders who dragged their feet to inform the public of the risks and to take decisive control measures

By Jeremy Page, Wenxin Fan and Natasha KhanMarch 6, 2020 10:36 am ET 

 https://www.wsj.com/articles/how-it-all-started-chinas-early-coronavirus-missteps-11583508932?mod=searchresults&page=6&pos=8 


 Mar 16, 2020 01:14 PM

Coronavirus Live Updates (Monday): Fed Cuts Rate to Near Zero; Deaths Outside China Hit More Than 3,200

 https://www.caixinglobal.com/2020-03-16/coronavirus-live-updates-monday-fed-cuts-rate-to-near-zero-deaths-outside-china-hit-more-than-3200-101529015.html 


  China CDC Weekly  > 2020, 2(4): 61-62

Notes from the Field: A Novel Coronavirus Genome Identified in a Cluster of Pneumonia Cases — Wuhan, China 2019−2020

 http://weekly.chinacdc.cn/en/article/id/a3907201-f64f-4154-a19e-4253b453d10c 


 

Younger adults less immune to Covid-19 health risks than thought, US agency’s study suggests

  • A top American health official and US President Donald Trump urged the country’s millennials to heed social distancing guidelines
  • Data from Centres for Disease Control and Prevention showed that a fifth of 705 people aged 20-44 were hospitalised, with 2-4 per cent requiring intensive care

Bhavan Jaipragas

Published: 6:01am, 19 Mar, 2020

 https://www.scmp.com/news/china/society/article/3075864/younger-adults-less-immune-covid-19-health-risks-thought-us 


 Mar 20, 2020 05:00 AMSOCIETY & CULTURE

Coronavirus Live Updates (Thursday): Italy’s Death Toll Surpasses China’s; India Bars Inbound Flights

 https://www.caixinglobal.com/2020-03-20/coronavirus-live-updates-thursday-china-reports-zero-domestically-produced-infections-trump-invokes-emergency-measures-to-ramp-up-mask-production-101530921.html 


 

When You Die of the Coronavirus, You Die Alone

Containing a pandemic means keeping visitors out of the I.C.U. My patients will suffer in solitary confinement.

By Daniela J. Lamas

Dr. Lamas is critical care doctor.

  • March 24, 2020, 5:00 a.m. ET

 https://www.nytimes.com/2020/03/24/opinion/coronavirus-hospital-visits.html 

number of people tested in US on 3/10/2020 for coronavirus = 8

Coronavirus: some recovered patients - reduced lung function & are gasping for air walking, HK docs

Coronavirus: China’s ravaged manufacturing heartlands force international firms to speed up exit

 

Testing in the U.S.

Updated March 11, 2020

This page will be updated regularly at noon Mondays through Fridays. Data close out at 4 p.m. the day before reporting.

CDC is responding to an outbreak of respiratory illness caused by a novel (new) coronavirus. The outbreak first started in Wuhan, China, but cases have been identified in a growing number of other locations internationally, including the United States.


number of people tested in US on 3/10/2020  for coronavirus =  8



 INFECTIOUS DISEASES  CORONAVIRUS (COVID-19)PRINT 

A Timeline of Coronavirus (COVID-19)

How It Started and Where It's Spreading

By Team Verywell  Fact checked by James Lacy Updated on March 12, 2020 

 https://www.verywellhealth.com/coronavirus-covid-19-timeline-4798671 


 

QIAGEN Gains BARDA Funding for Approval Process of QIAstat-Dx Test Kit for SARS-CoV-2 Coronavirus

Fri March 13, 2020 9:01 AM|Business Wire|About: QGEN

  • First syndromic testing solution to get U.S. agency’s development support in novel coronavirus response
  • QIAstat-Dx Respiratory SARS-CoV-2 Panel test kit will rapidly differentiate novel coronavirus from 21 other pathogens implicated in respiratory syndromes
  • Further expanding QIAGEN’s global mobilization to scale up testing supplies for the COVID-19 response

HILDEN, Germany & GERMANTOWN, Md.--(BUSINESS WIRE)-- QIAGEN (NYSE: QGEN; Frankfurt Prime Standard: QIA)

 https://seekingalpha.com/pr/17808834-qiagen-gains-barda-funding-for-approval-process-of-qiastat-dx-test-kit-for-sars-covminus-2  


 https://seekingalpha.com/symbol/QGEN 


 

Roche’s cobas SARS-CoV-2 Test to detect novel coronavirus receives FDA Emergency Use Authorization and is available in markets accepting the CE mark

  • First commercial test for SARS-CoV-2 will enable expedited coronavirus testing to meet urgent medical needs
  • Testing on widely available, high-volume cobas 6800/8800 will significantly increase available testing capacity
  • Roche expedites test development to support urgent need for patient testing during pandemic outbreak to avoid a further spread of the virus at an early stage of infection

Basel, 13 March 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY)

 https://www.roche.com/media/releases/med-cor-2020-03-13.htm


 https://seekingalpha.com/symbol/RHHBY


 

FDA Issues Emergency Use Authorization to Thermo Fisher Scientific for Diagnostic Test Used to Detect COVID-19

Fri March 13, 2020 10:09 PM|PR Newswire|About: TMO

WALTHAM, Mass., March 13, 2020 /PRNewswire/ -- Thermo Fisher Scientific Inc. (TMO)

 https://seekingalpha.com/pr/17809324-fda-issues-emergency-use-authorization-to-thermo-fisher-scientific-for-diagnostic-test-used 


 

TaqPath COVID-19 Multiplex Diagnostic Solution

 https://www.thermofisher.com/us/en/home/clinical/clinical-genomics/pathogen-detection-solutions/coronavirus-2019-ncov/genetic-analysis/taqpath-rt-pcr-covid-19-kit.html   


 

Roche begins shipments of first 400,000 COVID-19 tests to laboratories across US to begin patient testing under FDA Emergency Use Authorization

- Broad network of labs will use automated cobas SARS-CoV-2 Test to process high volume of patient samples sent from across US

- First available commercial test kit for novel coronavirus will enable labs to expand and expedite testing to meet urgent medical needs

 https://www.prnewswire.com/news-releases/roche-begins-shipments-of-first-400-000-covid-19-tests-to-laboratories-across-us-to-begin-patient-testing-under-fda-emergency-use-authorization-301025096.html 

 

cobas® SARS-CoV-2 Test

 https://diagnostics.roche.com/global/en/products/params/cobas-sars-cov-2-test.html 

 

Coronavirus: China’s ravaged manufacturing heartlands force international firms to speed up exit

Coronavirus: some recovered patients - reduced lung function & are gasping for air walking, HK docs

Coronavirus: China’s ravaged manufacturing heartlands force international firms to speed up exit

 Economy / China Economy

Coronavirus: China’s ravaged manufacturing heartlands force international firms to speed up exit strategies

  • Some multinationals are increasingly fleeing China, having seen the coronavirus outbreak as validation of exit strategies made during the US trade war
  • While some bemoan the lack of alternatives, others will stay for the domestic market as the supply chain debate rages on

Finbarr Bermingham

Published: 12:00pm, 5 Mar, 2020


 

Opinion

Minxin Pei

How China’s coronavirus crisis exposes the Achilles’ heel of Communist Party power

  • The party’s initial mishandling of the outbreak has eroded support among China’s urban middle class
  • The brief but intense eruption of public criticism is a taste of how such missteps can threaten the social contract on which the party’s legitimacy is built

Minxin Pei

Published: 12:30am, 6 Mar, 2020

https://www.scmp.com/comment/opinion/article/3065132/how-chinas-coronavirus-crisis-exposes-achilles-heel-communist-party 


 

Coronavirus: US Secretary of State Mike Pompeo switches disease name to ‘Wuhan virus’ as it spreads in the US

  • Top US diplomat ignores pleas from Beijing and world health officials over the use of names for the Covid-19 disease that incite racial discrimination
  • New nomenclature comes with President Donald Trump’s administration under fire over its response to community transmission of the virus in the US

Bhavan Jaipragas

Published: 4:58am, 7 Mar, 2020

https://www.scmp.com/news/china/politics/article/3074050/coronavirus-us-secretary-state-mike-pompeos-wuhan-virus 

 Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU) 

https://www.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6 

Addressing the potential impact of novel coronavirus disease (COVID-19) on medicines supply in the EU

ShareNews 10/03/2020 

https://www.ema.europa.eu/en/news/addressing-potential-impact-novel-coronavirus-disease-covid-19-medicines-supply-eu 

 Prognosis

Coronavirus Outbreak Likely Began With Bats, an Omen for Next Epidemic

Scientists say future pandemics are inevitable as cities and villages encroach on wild habitats

By

February 3, 2020, 3:38 PM EST Updated on February 3, 2020, 4:09 PM EST\

https://www.bloomberg.com/news/articles/2020-02-03/where-did-coronavirus-come-from-why-bats-may-be-to-blame 



 

Facts about novel coronavirus and how to prevent COVID-19

March 6, 2020 at 7:19 am Updated March 12, 2020 at 4:12 pm 

 https://www.seattletimes.com/seattle-news/health/facts-about-novel-coronavirus-and-how-to-prevent-covid-19/ 

 

Coronavirus: some recovered patients - reduced lung function & are gasping for air walking, HK docs

Coronavirus: some recovered patients - reduced lung function & are gasping for air walking, HK docs

Coronavirus: some recovered patients - reduced lung function & are gasping for air walking, HK docs

  Hong Kong / Health & Environment

Coronavirus: some recovered patients may have reduced lung function and are left gasping for air while walking briskly, Hong Kong doctors find

  • Hospital Authority releases its findings after observing the first group of discharged coronavirus patients
  • Some patients might have a drop of about 20 to 30 per cent in lung function, says medical director of Infectious Disease Centre at Princess Margaret Hospital

Elizabeth Cheung

Published: 12:04am, 13 Mar, 2020


 

Johnson & Johnson Announces Collaboration with the Beth Israel Deaconess Medical Center to Accelerate COVID-19 Vaccine Development

Fri March 13, 2020 9:41 AM|PR Newswire|About: JNJPR Newswire

NEW BRUNSWICK, N.J., March 13, 2020 /PRNewswire/ -- Johnson & Johnson (JNJ)

 https://seekingalpha.com/pr/17808870-johnson-johnson-announces-collaboration-beth-israel-deaconess-medical-center-to-accelerate 


 https://seekingalpha.com/symbol/JNJ


 

Can old drugs take down a new coronavirus?

Several approved and well-studied small molecules could be repurposed as treatments for COVID-19

by Lisa M. Jarvis
MARCH 12, 2020

C&EN has made this story and all of its coverage of the coronavirus epidemic freely available during the outbreak to keep the public informed. To support our journalism, become a member of ACS or sign up for C&EN's weekly newsletter.

 https://cen.acs.org/sections/coronavirus/biological-chemistry/infectious-disease/coronavirus-drug-repurposing.html  


 

Coronavirus: US infections likely to surge as mobile testing gets underway, officials say

  • Following in the footsteps of South Korea, ‘drive-through’ coronavirus diagnostic testing will be rolled out across the US in the coming days
  • President Donald Trump has told Americans who have been panic-buying supplies at grocery stores to ‘relax’ and ‘take it easy’

Bhavan Jaipragas

Published: 7:12am, 16 Mar, 2020

 https://www.scmp.com/news/world/united-states-canada/article/3075307/coronavirus-us-infections-likely-surge-mobile 


 Mar 16, 2020 04:17 AMWORLD

In Depth: How the U.S. Missed Its Window for Taming the Covid-19 Virus

By Zeng Jia, Ma Danmeng, Zhang Qi and Denise Jia 

 https://www.caixinglobal.com/2020-03-16/in-depth-how-the-us-missed-its-window-for-taming-the-covid-19-virus-101528836.html 


 Mar 18, 2020 01:56 PMBUSINESS & TECH

China Says Japan-Developed Drug Avigan Works Against Coronavirus

By Shin Watanabe 

 https://www.caixinglobal.com/2020-03-18/china-says-japan-developed-drug-avigan-works-against-coronavirus-101530182.html 


 

Japanese-Developed Flu Drug Avigan Seems Effective Against COVID-19

Early studies show the influenza treatment significantly shortens coronavirus illnesses and improves lung function in patients.

 https://www.fool.com/investing/2020/03/19/flu-drug-avigan-covid19-coronavirus.aspx 


 










Who is getting sick, and how sick? A breakdown of coronavirus risk by demographic factors

Who is getting sick, and how sick? A breakdown of coronavirus risk by demographic factors

Coronavirus: some recovered patients - reduced lung function & are gasping for air walking, HK docs

 HEALTH

Who is getting sick, and how sick? A breakdown of coronavirus risk by demographic factors

By SHARON BEGLEY @sxbegle

MARCH 3, 2020

 

Senior Writer, Science and Discovery

Sharon covers science and discovery.

sharon.begley@statnews.com @sxbegle 


 Mar 07, 2020 03:15 AMSOCIETY & CULTURE

In Depth: How Shanghai Handled the Coronavirus Better Than Most of China

By Ma Danmeng, Di Ning and Sun Huixia 

 https://www.caixinglobal.com/2020-03-07/in-depth-how-shanghai-handled-the-coronavirus-better-than-most-of-china-101525054.html 


 

Bloomberg 

Gilead Analyst Sees Only 50% Chance That Coronavirus Drug Works

By March 5, 2020, 9:19 AM EST 

 https://www.bloomberg.com/news/articles/2020-03-05/gilead-analyst-sees-only-50-chance-that-coronavirus-drug-works 


 https://www.bloomberg.com/quote/GILD:US 


 

 https://www.mayoclinic.org/diseases-conditions/coronavirus/symptoms-causes/syc-20479963 

coronavirus treatments or vaccines

Who is getting sick, and how sick? A breakdown of coronavirus risk by demographic factors

Remdesivir (GS-5734, Nuc inhibitor)

 

These nine companies are working on coronavirus treatments or vaccines — here’s where things stand

141Published: March 8, 2020 at 10:45 a.m. ETBy 

The list includes Gilead Sciences Inc. and Moderna Inc. along with smaller biotechs

 GILD

+5.37% 

GSK

-0.49% 

INO

+43.77% 

JNJ

+0.01% 

MRNA

+5.71% 

REGN

+1.28% 

SNY

-3.00% 

TAK

+0.78% 

VIR

+4.38% 


 https://www.worldometers.info/coronavirus/coronavirus-cases/#case-dayly-outchina 


 https://www.worldometers.info/coronavirus/#news 


 CBS NEWS March 8, 2020, 11:47 AM

Transcript: Scott Gottlieb on "Face the Nation," March 8, 2020

 https://www.cbsnews.com/news/transcript-scott-gottlieb-on-face-the-nation-march-8-2020/ 

Remdesivir (GS-5734, Nuc inhibitor)

Who is getting sick, and how sick? A breakdown of coronavirus risk by demographic factors

Remdesivir (GS-5734, Nuc inhibitor)

image165

 HEALTHCORONAVIRUS

Gilead’s coronavirus treatment is already being used in Washington state

BY SY MUKHERJEE

March 10, 2020 4:34 PM EST


 6,249 views|Mar 10, 2020,01:19pm EST

Buy Gilead...But Not Because Of Remdesivir

James BermanContributorInvestingI look for value wherever I can find it, both in stocks and in life. 

 https://www.forbes.com/sites/jamesberman/2020/03/10/buy-gileadbut-not-because-of-remdesivir/#330f870e20d5 


 

Experimental Drug Helps Some Americans Ride Out Coronavirus, NIH Doctor Says

Antiviral drug remdesivir appeared to have an effect in American cruise passengers treated in Japan, although data are limited

By Suryatapa BhattacharyaUpdated March 13, 2020 7:52 am ET 

 https://www.wsj.com/articles/experimental-drug-helps-some-americans-ride-out-coronavirus-nih-doctor-says-11584094955 


 OPINION

YOUNG AND UNAFRAID OF THE CORONAVIRUS PANDEMIC? GOOD FOR YOU. NOW STOP KILLING PEOPLE | OPINION

A DOCTOR IN WESTERN EUROPE
ON 3/11/20 AT 2:29 PM EDT 

 https://www.newsweek.com/young-unafraid-coronavirus-pandemic-good-you-now-stop-killing-people-opinion-1491797?fbclid=IwAR0PC4PSWvKP8c7dz0jmvGrKjadfNfn5d8n9wabRFMRti2WV6GJbFGyq0OM 

 

Mild/Moderate 2019-nCoV Remdesivir RCT

 https://clinicaltrials.gov/ct2/show/NCT04252664?term=Remdesivir&draw=2&rank=2 

 

Severe 2019-nCoV Remdesivir RCT

 https://clinicaltrials.gov/ct2/show/NCT04257656 



novel coronavirus (2019-nCoV) 病毒:新型冠状病毒 2019-nCoV

IPhone Maker Projects China Plants to Return to Normal in Coming Weeks

Coronavirus outbreak fans the flames of US-China decoupling debate in Washington

Coronavirus outbreak fans the flames of US-China decoupling debate in Washington

 Mar 04, 2020 06:24 AMBUSINESS & TECH

IPhone Maker Projects China Plants to Return to Normal in Coming Weeks

 (Bloomberg) — Hon Hai Precision Industry Co., Apple Inc.’s most important manufacturing partner, said it expects its Chinese plants to begin operating normally by the end of March after resolving severe labor shortages brought on by the coronavirus outbreak


 

Coronavirus could cause global medicine shortages as China’s factory closures hit supply chains

  • Factory activity in China – the top producer of active pharmaceutical ingredients – hit all-time low in February after measures to halt outbreak
  • US and Europe monitoring short-term delay to supplies, with antibiotics, diabetes medications, HIV drugs and ibuprofen among those heavily reliant on China

Simone McCarthy

Published: 3:46pm, 4 Mar, 2020

 https://www.scmp.com/news/china/society/article/3064989/coronavirus-could-cause-global-medicine-shortages-chinas-factory 


 

Coronavirus: ‘Recovered’ patient dies as China reports discharged cases falling ill again

  • A 36-year-old man has died in Wuhan from respiratory failure days after being discharged from hospital
  • Latest data from the mainland shows most new infections continue to occur at epidemic’s epicentre

Gigi Choy and Teddy Ng

Published: 9:23am, 5 Mar, 2020

 https://www.scmp.com/news/china/society/article/3065091/coronavirus-recovered-patient-dies-china-reports-139-new-cases 

Coronavirus outbreak fans the flames of US-China decoupling debate in Washington

Coronavirus outbreak fans the flames of US-China decoupling debate in Washington

Coronavirus outbreak fans the flames of US-China decoupling debate in Washington

 Economy / China Economy

Coronavirus outbreak fans the flames of US-China decoupling debate in Washington

  • Any hope that the US-China phase one trade deal would salvage the superpower relationship have been scotched by the coronavirus
  • Epidemic set to hit US economy and has led to rising discord among Washington figures, some of whom call for decoupling between the world’s two largest economies

Cissy Zhou

Published: 6:00am, 4 Mar, 2020


 Mar 03, 2020 08:53 PMOPINION

Opinion: A Pandemic of Deglobalization?

By Harold James
 

 https://www.caixinglobal.com/2020-03-03/opinion-a-pandemic-of-deglobalization-101523519.html 


 Mar 05, 2020 08:08 PMOPINION

Opinion: Make Careful Supply Chain Decisions for the Future, Not the Past

By Edward Tse 

 https://www.caixinglobal.com/2020-03-05/opinion-make-careful-supply-chain-decisions-for-the-future-not-the-past-101524487.html 

Are temperature checks effective in stopping the spread of the coronavirus?

Coronavirus outbreak fans the flames of US-China decoupling debate in Washington

Lights Are On but No One’s Working: How Local Governments Are Faking Coronavirus Recovery

image166

 

Are temperature checks effective in stopping the spread of the coronavirus?

  • Use of ‘temperature guns’ is increasingly common as authorities and companies screen people entering buildings
  • Questions remain over transmission by people who have not shown symptoms

Gigi Choy

Published: 7:45am, 4 Mar, 2020

 

06:26 AMSOCIETY & CULTURE

Five Provinces Find Recovered Patients Testing Positive for Covid-19

By Cui Xiankang and Denise Jia 0-03-04/covid-19-virus-found-in-two-more-recovered-patients-in-tianjin-101523652.html 

 https://www.caixinglobal.com/2020-03-04/covid-19-virus-found-in-two-more-recovered-patients-in-tianjin-101523652.html 

 

Coronaviruses: an overview of their replication and pathogenesis.

 https://www.ncbi.nlm.nih.gov/pubmed/25720466 

Lights Are On but No One’s Working: How Local Governments Are Faking Coronavirus Recovery

Lights Are On but No One’s Working: How Local Governments Are Faking Coronavirus Recovery

Lights Are On but No One’s Working: How Local Governments Are Faking Coronavirus Recovery

image167

 Mar 04, 2020 08:28 PMBUSINESS & TECH

Lights Are On but No One’s Working: How Local Governments Are Faking Coronavirus Recovery

By Yuan Ruiyang and Isabelle Li 


 Mar 04, 2020 09:52 PMSOCIETY & CULTURE

Coronavirus Live Updates (Wednesday): Iran Furloughs 54,000 Prisoners to Stop Spread in Jails; Chinese Car Sales Crushed

 https://www.caixinglobal.com/2020-03-04/coronavirus-live-updates-wednesday-new-china-cases-keep-falling-who-says-virus-spreads-less-efficiently-than-flu-101523878.html 


Coronavirus/COVID-19

Lights Are On but No One’s Working: How Local Governments Are Faking Coronavirus Recovery

Remdesivir (GS-5734, Nuc inhibitor)

 

The Trump Administration’s Many Vacancies Could Complicate its Coronavirus Response

 BY VERA BERGENGRUEN AND BRIAN BENNETT

UPDATED: FEBRUARY 27, 2020 8:59 PM EST | ORIGINALLY PUBLISHED: FEBRUARY 27, 2020 5:05 PM EST


 

Trump defends huge cuts to the CDC's budget by saying the government can hire more doctors 'when we need them' during crises

Joseph Zeballos-Roig Feb. 27, 2020, 10:45 AM 

 https://markets.businessinsider.com/news/stocks/trump-defends-cuts-cdc-budget-federal-government-hire-doctors-coronavirus-2020-2-1028946602


 

Welcome to the2019 Global Health Security Index 

 https://www.ghsindex.org/ 


 GLOBAL MONITORING OF DISEASE OUTBREAK PREPAREDNESS Preventing the Next Pandemic A Shared Framework 

 © 2018 Harvard Global Health Ins6tute 42 Church Street Cambridge, MA 02138 This work is the product of faculty and staff from the Harvard Global Health Ins6tute with major contribu6ons from Georgetown University Center for Global Health Science and Security and the John F. Kennedy School of Government at Harvard University. Suggested cita,on Harvard Global Health Ins6tute. 2018. Global Monitoring of Disease Outbreak Preparedness: Preven7ng the Next Pandemic. Harvard University, Cambridge, MA. 

 https://globalhealth.harvard.edu/files/hghi/files/global_monitoring_report.pdf 

Remdesivir (GS-5734, Nuc inhibitor)

Lights Are On but No One’s Working: How Local Governments Are Faking Coronavirus Recovery

Remdesivir (GS-5734, Nuc inhibitor)

 

The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus

  1. Calvin J Gordon1, 
  2. Egor P Tchesnokov1, 
  3. Joy Y. Feng2, 
  4. Danielle P Porter3 and 
  5. Matthias Gotte4*

+Author Affiliations

 

  • Received February 14, 2020.
  • Accepted February 24, 2020.
  • Published under license by The American Society for Biochemistry and Molecular Biology, Inc. 

Mechanism of action revealed for remdesivir, potential coronavirus drug

Researchers have demonstrated how the drug known as remdesivir works, presenting the viral RNA polymerase of coronaviruses as a target for these conditions.


 25 FEBRUARY 2020 NEWS

WHO says Gilead’s remdesivir may help treat coronavirus

 https://www.pharmaceutical-technology.com/news/who-gilead-remdesivir-coronavirus/ 


 

A closer look at the Ebola drug that's become the top hope for a coronavirus treatment

 

AUTHOR

@NedPagliarulo 

 https://www.biopharmadive.com/news/coronavirus-remdesivir-gilead-antiviral-drug-covid-19/573261/ 


 

Mild/Moderate 2019-nCoV Remdesivir RCT

 Sponsor:

Capital Medical University

Collaborator:

Chinese Academy of Medical Sciences

Information provided by (Responsible Party):

Bin Cao, China-Japan Friendship Hospital

 https://clinicaltrials.gov/ct2/show/NCT04252664?intr=GS-5734&draw=2&rank=5 

novel coronavirus (2019-nCoV) 病毒:新型冠状病毒 2019-nCoV

What the new phase of the coronavirus outbreak in the U.S. means for you

Report of the WHO-China joint mission on COVID-19 chinadaily.com.cn | Updated: 2020-03-02 06:30

What the new phase of the coronavirus outbreak in the U.S. means for you

 

What the new phase of the coronavirus outbreak in the U.S. means for you

Health experts warn there are probably many undetected COVID-19 cases already here

By Tina Hesman Saey, Aimee Cunningham and Erin Garcia de Jesus

FEBRUARY 28, 2020 AT 1:25 PM

UPDATED FEBRUARY 28, 2020 AT 8:45 PM


 

Coronavirus: first Chinese province that declared top-level emergency downgrades alert status

  • Zhejiang province, which is China’s key export and manufacturing base, declared a Grade I emergency on January 23, a day before the epicentre of Hubei
  • According to the Zhejiang Health Commission, there have been no new confirmed cases of the coronavirus in the province for nine days

Karen Yeung

Published: 5:45pm, 2 Mar, 20

 https://www.scmp.com/economy/china-economy/article/3064625/coronavirus-first-chinese-province-declare-top-level 

Coronavirus/COVID-19

Report of the WHO-China joint mission on COVID-19 chinadaily.com.cn | Updated: 2020-03-02 06:30

What the new phase of the coronavirus outbreak in the U.S. means for you

 

Coronavirus: Xi Jinping focuses on long-term battle as more countries report cases

  • Number of new infections in mainland China falls to lowest level since it locked down cities at centre of epidemic in January
  • EU raises risk level to ‘moderate to high’ as death toll in Europe from Covid-19 reaches 38

Teddy Ng, Gigi Choy, Simone McCarthy and Jevans Nyabiage

Published: 11:25pm, 2 Mar, 2020


 Mar 02, 2020 08:45 PMSOCIETY & CULTURE

Coronavirus Live Updates (Monday): Top Iranian Official Dies as South Korea Caseload Keeps Growing

 https://www.caixinglobal.com/2020-03-02/coronavirus-monday-updates-fear-grows-in-europe-as-new-cases-keep-falling-in-china-101522753.html 

Report of the WHO-China joint mission on COVID-19 chinadaily.com.cn | Updated: 2020-03-02 06:30

Report of the WHO-China joint mission on COVID-19 chinadaily.com.cn | Updated: 2020-03-02 06:30

Report of the WHO-China joint mission on COVID-19 chinadaily.com.cn | Updated: 2020-03-02 06:30

image168

 

Graphic: Report of the WHO-China joint mission on COVID-19

chinadaily.com.cn | Updated: 2020-03-02 06:30 

 http://global.chinadaily.com.cn/a/202003/02/WS5e5c376aa31012821727b644.html 


 

How Does the Coronavirus Compare With the Flu?

As new cases appear on the West Coast, some — including the president — are comparing it to the seasonal flu. Here’s a close look at the differences.

By Denise Grady Feb. 29, 2020

 https://www.nytimes.com/2020/02/29/health/coronavirus-flu.html?nl=todaysheadlines&emc=edit_th_200302&campaign_id=2&instance_id=16390&segment_id=21779&user_id=84cb7b8c76cc94fe5963a793a541483c&regi_id=577141640302 


Remdesivir (GS-5734, Nuc inhibitor)

Remdesivir (GS-5734, Nuc inhibitor)

Report of the WHO-China joint mission on COVID-19 chinadaily.com.cn | Updated: 2020-03-02 06:30

  

Chinese biotech firm censured for false claim on Gilead’s virus drug

  • BrightGene Bio-Medical Technology has not been licensed by Gilead to make its experimental drug known as remdesivir

Bloomberg

Published: 7:01pm, 2 Mar, 2020

 https://www.scmp.com/tech/big-tech/article/3064647/chinese-biotech-firm-censured-false-claim-gileads-virus-drug 

 

Look Out for Coronavirus-Related Investment Scams - Investor Alert

Feb. 4, 2020

The SEC’s Office of Investor Education and Advocacy is issuing this Investor Alert to warn investors about investment frauds involving claims that a company’s products or services will be used to help stop the coronavirus outbreak.

 https://www.sec.gov/oiea/investor-alerts-and-bulletins/ia_coronavirus 


 

Chinese Biotech Censured for False Claim on Gilead’s Virus Drug

Bloomberg NewsBloombergMarch 1, 2020 

 https://finance.yahoo.com/news/chinese-biotech-censured-false-claim-040207427.html 


 

  1. COVID-19
  2. CHINESE BIOTECH COMPANY CENSURED FOR CLAIMING IT COULD MAKE EXPERIMENTAL CORONAVIRUS DRUG 

Chinese Biotech Company Censured for Claiming It Could Make Experimental Coronavirus Drug

 

BY BLOOMBERG

MARCH 2, 2020 1:47 AM EST

 https://time.com/5793357/china-company-censured-coronavirus/ 


 

First Case of 2019 Novel Coronavirus in the United States

 ORIGINAL ARTICLEBRIEF REPORT 

 https://www.nejm.org/doi/full/10.1056/NEJMoa2001191 


Biotech-Wars™ – Hunger + Thirst

Remdesivir (GS-5734, Nuc inhibitor)

Biotech-Wars™ – Hunger + Thirst

image169

 

Biotech-Wars™ – Hunger + Thirst

Feb. 29, 2020 12:46 PM ET|About: AbbVie Inc. (ABBV), GILD, JNJ, MRNA, REGN, VIR, WXXWY

 danwatson888's Blog

long only, Deep Value, dividend growth investing, healthcare

Summary

the news coming from China since January 11, 2020 was never positive even if the actual reported statistical data was suspect.

everyone, including everyone in China, has a right to be angry about COVID-19.

too much single source product manufacturing located in China.

politicos are now creating “Anti-Endorsements” lists that identify successful USA citizens.

Covid-19

Remdesivir (GS-5734, Nuc inhibitor)

Biotech-Wars™ – Hunger + Thirst

EDITORIAL

Covid-19 — Navigating the Uncharted

List of authors.

  • Anthony S. Fauci, M.D., 
  • H. Clifford Lane, M.D., 
  • and Robert R. Redfield, M.D.

 February 28, 2020
DOI: 10.1056/NEJMe2002387 


 

 https://www.cdc.gov/flu/treatment/whatyoushould.htm 


 | VOLUME 395, ISSUE 10223, P507-513, FEBRUARY 15, 2020

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

Published:January 30, 2020 

 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30211-7/fulltext 

novel coronavirus (2019-nCoV) 病毒:新型冠状病毒 2019-nCoV

First death from coronavirus in the United States

We used two drugs: lopinavir / ritonavir, an antiviral used for HIV infection; and remdesivir

We used two drugs: lopinavir / ritonavir, an antiviral used for HIV infection; and remdesivir

 

First death from coronavirus in the United States confirmed in Washington state, officials say

By Christina Maxouris and Dakin Andone, CNN

Updated 4:12 PM ET, Sat February 29, 2020


 Washington State Is Investigating Potential Outbreak at Facility

2/29/2020, 4:39:25 PM 

 https://www.bloomberg.com/news/articles/2020-02-29/washington-state-is-investigating-potential-outbreak-at-facility?srnd=premium 


 

COVID-19 CORONAVIRUS OUTBREAK

Last updated: March 01, 2020, 01:32 GMT

 https://www.worldometers.info/coronavirus/ 


 Coronavirus disease 2019 (COVID-19) Situation Report – 31 

 https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200220-sitrep-31-covid-19.pdf?sfvrsn=dfd11d24_2  


 

As CDC warns of US COVID-19 spread, labs frustrated over lack of tests

Filed Under: COVID-19Stephanie Soucheray | News Reporter | CIDRAP News  | Feb 25, 2020 



 http://www.cidrap.umn.edu/news-perspective/2020/02/cdc-warns-us-covid-19-spread-labs-frustrated-over-lack-tests 


We used two drugs: lopinavir / ritonavir, an antiviral used for HIV infection; and remdesivir

We used two drugs: lopinavir / ritonavir, an antiviral used for HIV infection; and remdesivir

We used two drugs: lopinavir / ritonavir, an antiviral used for HIV infection; and remdesivir

 

The scientific director of the Spallanzani hospital: "Less infections out of Italy because the method is different"

Giuseppe Ippolito: «The administration of the test to patients who do not show symptoms does not comply with European guidelines»


 You made a new miracle with the two Chinese patients. Are the medications you used the weapon to fight the virus?
« We used two drugs: lopinavir / ritonavir, an antiviral commonly used for HIV infection and which also shows antiviral activity on coronaviruses; and remdesivir, an antiviral already used for Ebola, potentially active against new coronavirus infection. Our patients have recovered from pneumonia and have become negative compared to the virus, but more in-depth studies will be needed to verify whether this therapeutic approach can be extended ".  


 

Remdesivir (GS-5734, Nuc inhibitor)

https://www.gilead.com/science-and-medicine/pipeline 


 https://seekingalpha.com/symbol/GILD 


 

What are KALETRA® (lopinavir/ritonavir) tablets and oral solution?2

KALETRA is a prescription medicine that is used with other antiretroviral medicines to treat human immunodeficiency virus-1 (HIV-1) infection in adults and children 14 days of age and older. HIV is the virus that causes AIDS (acquired immune deficiency syndrome). It is not known if KALETRA is safe and effective in children under 14 days old.

https://www.kaletra.com/?cid=ppc_ppd_kaletra_ggl_br_0140 

 https://seekingalpha.com/symbol/ABBV  


 

AbbVie Products List

 https://www.abbvie.com/our-science/products.html 

Biotech-Wars™ – Hunger + Thirst

We used two drugs: lopinavir / ritonavir, an antiviral used for HIV infection; and remdesivir

Coronavirus: baby in South Korea infected as US, Australia and Thailand report first deaths

 

Politico’s continue to attack biotech/pharma companies even in the face of a pandemic with COVID-19


 Summary

the news coming from China since January 11, 2020 was never positive even if the actual reported statistical data was suspect.

everyone, including everyone in China, has a right to be angry about COVID-19.

too much single source product manufacturing located in China.

politicos are now creating “Anti-Endorsements” lists that identify successful USA citizens.

 Feb. 29, 2020 12:46 PM ET|About: AbbVie Inc. 

 danwatson888's Blog

long only, Deep Value, dividend growth investing, healthcare

(ABBV), GILD

GILD
Gilead Sciences, Inc.
, JNJ, MRNA, REGN, VIR, WXXWY 


 

Gilead Sciences Update On The Company’s Ongoing Response To COVID-19

 https://www.gilead.com/purpose/advancing-global-health/covid-19 

Coronavirus: baby in South Korea infected as US, Australia and Thailand report first deaths

Coronavirus: baby in South Korea infected as US, Australia and Thailand report first deaths

Coronavirus: baby in South Korea infected as US, Australia and Thailand report first deaths

 

Coronavirus: baby in South Korea infected as US, Australia and Thailand report first deaths

  • Total cases in South Korea reach 3,526, but estimates of 4,200 infections among Shincheonji church members alone
  • Cases rise in Hubei epicentre, but 3 new infections in the rest of mainland China is the lowest figure since lockdowns began on January 23

Teddy Ng and Amanda Lee in Beijing

Published: 9:55am, 1 Mar, 2020


 

Prisons, retirement homes are weak links: Hubei chief

Hubei’s new Communist Party chief Ying Yong told a local virus response meeting he chaired on Saturday that the outbreak was still at a “critical” stage in the province, despite some progress in containing the epidemic.

He said the government needed to improve efforts to prevent new infections in prisons and pensioners’ homes, where there have been outbreaks in recent days.

 https://www.scmp.com/news/china/society/article/3053048/coronavirus-south-korea-expects-surge-shincheonji-church 


 Feb 25, 2020 08:50 PMSOCIETY & CULTURE

Guangzhou Family Cluster Appears to Experience Extra-Long Covid-19 Incubation

By Huang Shulun and Dave Yin 

 https://www.caixinglobal.com/2020-02-25/guangzhou-family-cluster-appears-to-experience-extra-long-covid-19-incubation-101520343.html 

"Coronavirus is a moving target"

Coronavirus: baby in South Korea infected as US, Australia and Thailand report first deaths

Coronavirus: Hong Kong expert claims outbreak is now a pandemic

image170

 

Uncertainty in a Time of Coronavirus

Here’s why communicating public health risk during an epidemic is so challenging

" Coronavirus is a moving target, as most epidemics are."



 

GLOBAL HEALTH

Wuhan Coronavirus Looks Increasingly Like a Pandemic, Experts Say

Rapidly rising caseloads alarm researchers, who fear the virus may make its way across the globe. But scientists cannot yet predict how many deaths may result.

 https://www.nytimes.com/2020/02/02/health/coronavirus-pandemic-china.html 


 Opinion

Is It a Pandemic Yet?

It’s now clear that the coronavirus epidemic was never going to be contained. What’s next?

By Michael T. Osterholm and Mark Olshaker

Mr. Osterholm is an infectious disease expert. Mark Olshaker is a writer and documentary filmmaker.

  • Feb. 24, 2020

阅读简体中文版閱讀繁體中文版 

 https://www.nytimes.com/2020/02/24/opinion/coronavirus-pandemic.html 


 

As work resumes in outbreak, brand-new 'normal' emerges

By Cao Zinan and Li Danqing | chinadaily.com.cn | Updated: 2020-03-01 06:30 

 http://global.chinadaily.com.cn/a/202003/01/WS5e5ae5e8a31012821727b4c1.html 

Coronavirus: Hong Kong expert claims outbreak is now a pandemic

Coronavirus: baby in South Korea infected as US, Australia and Thailand report first deaths

Coronavirus: Hong Kong expert claims outbreak is now a pandemic

 Hong Kong / Health & Environment

Coronavirus: Hong Kong expert claims outbreak is now a pandemic and US death could be ‘tip of the iceberg’

  • University of Hong Kong’s medical faculty dean Gabriel Leung says only reason WHO has not used word is ‘public fear’
  • First wave of outbreak outside China could just be starting, says Leung

Tony Cheung

Published: 12:47pm, 1 Mar, 2020


 

FEB. 28, 2020, AT 10:13 AM

Quarantines Won’t Save Us From Coronavirus

By

Filed under Coronavirus

 https://fivethirtyeight.com/features/quarantines-wont-save-us-from-coronavirus/ 


 POLITICSMARCH 1, 2020 / 10:00 AM / UPDATED 2 HOURS AGO

Coronavirus spurs U.S. to screen travelers, ramp up mask production after first death

 https://www.reuters.com/article/us-china-health-usa/coronavirus-spurs-u-s-to-screen-travelers-ramp-up-mask-production-after-first-death-idUSKBN20O1WF 

novel coronavirus (2019-nCoV) 病毒:新型冠状病毒 2019-nCoV

China’s coronavirus epidemic shows strengths, flaws of one country, one system

Economists try to estimate the impact of a pandemic, but we just don’t know how bad it could get

China’s coronavirus epidemic shows strengths, flaws of one country, one system

 

China’s coronavirus epidemic shows strengths, flaws of one country, one system

  • The system allows Beijing to mobilise vast resources and take steps that would be unthinkable in the West
  • But critics say the top-down system encourages cover-ups and repeated missteps in the face of a crisis

Jun Mai

Published: 7:30am, 28 Feb, 2020


 Feb 27, 2020 08:56 PMSOCIETY & CULTURE

Coronavirus Thursday Update: WHO Says Coronavirus Outbreak at ‘Decisive Point’; Iran Vice President Tested Positive

 https://www.caixinglobal.com/2020-02-27/coronavirus-thursday-update-new-international-infections-surpass-china-infections-101521174.html 



Will COVID-19 go away on its own in warmer weather?

Economists try to estimate the impact of a pandemic, but we just don’t know how bad it could get

China’s coronavirus epidemic shows strengths, flaws of one country, one system

 

Will COVID-19 go away on its own in warmer weather?

Marc Lipsitch, DPhil
Professor of Epidemiology and Director, Center for Communicable Disease Dynamics, Harvard T.H. Chan School of Public Health

(tl;dr) No.


 

The Coronavirus Scare: This Time Is Different

Even if health authorities get a grip on the outbreaks, counting on an economic and market recovery may be wishful thinking

 By Spencer Jakab, 

Stephen Wilmot and Justin LahartFeb. 25, 2020 7:00 am ET 

 https://www.wsj.com/articles/the-coronavirus-scare-this-time-is-different-11582632012?mod=article_inline 


 Feb 28, 2020 06:25 PMSOCIETY & CULTURE

In Depth: How Early Signs of a SARS-Like Virus Were Spotted, Spread, and Throttled

By Gao Yu, Peng Yanfeng, Yang Rui, Feng Yuding, Ma Danmeng, Flynn Murphy, Han Wei and Timmy Shen 

 https://www.caixinglobal.com/2020-02-28/in-depth-how-early-signs-of-a-sars-like-virus-were-spotted-spread-and-throttled-101521745.html 

Economists try to estimate the impact of a pandemic, but we just don’t know how bad it could get

Economists try to estimate the impact of a pandemic, but we just don’t know how bad it could get

Economists try to estimate the impact of a pandemic, but we just don’t know how bad it could get

 

Opinion: If the coronavirus isn’t contained, a severe global recession is almost certain

Published: Feb 25, 2020 9:09 a.m. ET

By

COLUMNIST 


 

Coronavirus: China, Japan, South Korea supply chains under threat from ‘second wave’ of disruptions

  • The three Asian countries contribute around 24 per cent of the entire world economy, but have been hit hard by the coronavirus outbreak
  • China was attempting to boost trade and investment with Japan and South Korea to offset risks of decoupling from the United States

Orange Wang

Published: 9:15pm, 27 Feb, 2020

 https://www.scmp.com/economy/china-economy/article/3052646/coronavirus-china-japan-south-korea-supply-chains-under 


 Feb 29, 2020 04:25 PMOPINION

Opinion: Five Lessons for Other Nations from China’s Fight Against Covid-19

By Wang Shuo 

 https://www.caixinglobal.com/2020-02-29/opinion-five-lessons-for-other-nations-from-chinas-fight-against-covid-19-101522191.html 

Health experts warned of a epidemic = ‘threatening to the world and socially disrupting’.

Health experts warned of a epidemic = ‘threatening to the world and socially disrupting’.

Economists try to estimate the impact of a pandemic, but we just don’t know how bad it could get

 

How Disease X, the epidemic-in-waiting, erupted in China

Health experts warned of a future epidemic that would be ‘threatening to the world and socially disrupting’. The new virus may fit the description

PUBLISHED 27 FEBRUARY, 2020
ILLUSTRATIONS BY KALIZ LEE

By Simone McCarthy, Linda Lew, William Zheng, Echo Xie and Phoebe Zhang

 

South China Morning Post

 https://multimedia.scmp.com/infographics/news/china/article/3052721/wuhan-killer/index.html?src=pm 


 

Infections across world now top WHO's concerns

By CHEN WEIHUA in Brussels | China Daily | Updated: 2020-02-29 03:44 

 http://global.chinadaily.com.cn/a/202002/29/WS5e596da8a31012821727b304.html 

Epidemic's impact on China's place in supply chains should be minimal: MoC

Health experts warned of a epidemic = ‘threatening to the world and socially disrupting’.

Epidemic's impact on China's place in supply chains should be minimal: MoC

 

Epidemic's impact on China's place in supply chains should be minimal: MoC

By Zhong Nan | chinadaily.com.cn | Updated: 2020-02-27 17:37

 http://global.chinadaily.com.cn/a/202002/27/WS5e578ddfa31012821727ad99.html 


 

Coronavirus: Vietnam lured factories during trade war, but now faces big hit as parts from China stop flowing

  • Vietnam became the destination of choice for firms looking to avoid trade war tariffs, but the coronavirus has left many cut off from their suppliers
  • The Southeast Asian nation is more exposed to China’s supply chain than any other country in region, research shows, with companies across the board set to take a hit

Finbarr Bermingham

Published: 1:02pm, 28 Feb, 2020

 https://www.scmp.com/economy/china-economy/article/3052823/coronavirus-vietnam-lured-factories-during-trade-war-now 

'Smart hospital' plays important role in virus prevention

Health experts warned of a epidemic = ‘threatening to the world and socially disrupting’.

Epidemic's impact on China's place in supply chains should be minimal: MoC

 

Novel heroes: 'Smart hospital' plays important role in virus prevention

chinadaily.com.cn | Updated: 2020-02-28 13:09 

 http://global.chinadaily.com.cn/a/202002/28/WS5e58a073a31012821727b129.html 


 

Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19

Published:February 19, 2020DOI:https://doi.org/10.1016/S0140-6736(20)30418-9 

 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30418-9/fulltext 

novel coronavirus (2019-nCoV) 病毒:新型冠状病毒 2019-nCoV

Remdesivir (GS-5734, Nuc inhibitor)

Past Time to Tell the Public: “It Will Probably Go Pandemic, and We Should All Prepare Now”

Past Time to Tell the Public: “It Will Probably Go Pandemic, and We Should All Prepare Now”

 February 25, 2020 09:11 AM EST Jason Mast R&DCoronavirus

First US Covid-19 tri­als set to get un­der­way in Ne­bras­ka and Wash­ing­ton, backed by NIH

 

Tuesday, February 25, 2020

NIH clinical trial of remdesivir to treat COVID-19 begins

Study enrolling hospitalized adults with COVID-19 in Nebraska.

 https://www.nih.gov/news-events/news-releases/nih-clinical-trial-remdesivir-treat-covid-19-begins 


 

LEFT

RIGHT

8 OF 10

READ ALL TODAY'S ISSUE IN FULL

TODAY'S ISSUE

NIH starts testing Gilead’s remdesivir as treatment for COVID-19

 26-02-2020 

 https://www.thepharmaletter.com/article/nih-starts-testing-gilead-s-remdesivir-as-treatment-for-covid-19 


 

Gilead to Expand Coronavirus Drug Trials to Other Countries

The drug maker said that in March it would begin two more clinical trials of remdesivir, an experimental antiviral drug, in more nations outside China.

 https://www.nytimes.com/2020/02/26/health/coronavirus-gilead-drug-trials.html 


 

Gilead Sciences Update On The Company’s Ongoing Response To COVID-19

 https://www.gilead.com/purpose/advancing-global-health/covid-19 

Past Time to Tell the Public: “It Will Probably Go Pandemic, and We Should All Prepare Now”

Past Time to Tell the Public: “It Will Probably Go Pandemic, and We Should All Prepare Now”

Past Time to Tell the Public: “It Will Probably Go Pandemic, and We Should All Prepare Now”

image171

 

Past Time to Tell the Public: “It Will Probably Go Pandemic, and We Should All Prepare Now”

Posted onFebruary 23, 2020AuthorIan M Mackay, PhD (EIC)107 Comments

by Jody Lanard and Peter M. Sandman

 https://virologydownunder.com/past-time-to-tell-the-public-it-will-probably-go-pandemic-and-we-should-all-prepare-now/ 


 China / Society

Big unknowns for millions as they return to work in China’s economic powerhouse

  • Some people are struggling to get back to their workplaces while those who can face quarantine and financial uncertainties
  • Businesses are also feeling the squeeze as they try to absorb the cost of extra protective equipment and measures.

Guo Rui

Published: 8:00am, 26 Feb, 2020

 https://www.scmp.com/news/china/society/article/3052329/big-unknowns-millions-they-return-work-chinas-economic 


14% of Recovered Covid-19 Patients in Guangdong Tested Positive Again

Past Time to Tell the Public: “It Will Probably Go Pandemic, and We Should All Prepare Now”

TNX-1800* (live modified horsepox virus vaccine for percutaneous administration)

 Feb 26, 2020 06:47 AMSOCIETY & CULTURE

14% of Recovered Covid-19 Patients in Guangdong Tested Positive Again

By Li Liuqian, Huang Shulun and Han Wei 

 https://www.caixinglobal.com/2020-02-26/14-of-recovered-covid-19-patients-in-guangdong-tested-positive-again-101520415.html 


 

Coronavirus far more likely than Sars to bond to human cells due to HIV-like mutation, scientists say

  • Research by team from Nankai University shows new virus has mutated gene similar to those found in HIV and Ebola
  • Finding may help scientists understand how the infection spreads and where it came from

Stephen Chen in Beijing

Published: 12:30am, 27 Feb, 2020

 https://www.scmp.com/news/china/society/article/3052495/coronavirus-far-more-likely-sars-bond-human-cells-scientists-say 

TNX-1800* (live modified horsepox virus vaccine for percutaneous administration)

Vir Biotechnology & WuXi Biologics Collaboration for Development of Antibodies to Treat COVID-19

TNX-1800* (live modified horsepox virus vaccine for percutaneous administration)

image172

 

Tonix Pharmaceuticals Announces Research Collaboration with Southern Research to Develop a Potential Vaccine to Protect Against New Coronavirus Disease 2019 (COVID-19) Based on Horsepox Virus (TNX-1800)

Wed February 26, 2020 7:00 AM|GlobeNewswire|About: TNXP

NEW YORK, Feb. 26, 2020 (GLOBE NEWSWIRE) -- Tonix Pharmaceuticals Holding Corp. (TNXP


 https://www.tonixpharma.com/ 


 https://www.tonixpharma.com/pipeline/overview 


 https://southernresearch.org/ 


 

SOUTHERN RESEARCH, TONIX TEAM TO DEVELOP POTENTIAL VACCINE AGAINST NEW CORONAVIRUS

FEBRUARY 26, 2020 | BY JERRY UNDERWOOD | DRUG DEVELOPME 

 https://southernresearch.org/news/southern-research-tonix-team-to-develop-potential-vaccine-against-new-coronavirus/ 


 https://seekingalpha.com/symbol/TNXP 



Gilead Granted Three Chinese Patents for Antiviral Drug Remdesivir (GS-5734, Nuc inhibitor)

Vir Biotechnology & WuXi Biologics Collaboration for Development of Antibodies to Treat COVID-19

Vir Biotechnology & WuXi Biologics Collaboration for Development of Antibodies to Treat COVID-19

 Feb 26, 2020 10:24 PMSOCIETY & CULTURE

Coronavirus Wednesday Update: Another 284 Cases Reported in South Korea; Gilead Granted Three Chinese Patents for Antiviral Drug Remdesivir

 https://www.caixinglobal.com/2020-02-26/coronavirus-wednesday-update-switzerland-austria-brazil-sound-alarm-on-first-cases-101520678.html 


 

Antiviral drug Remdesivir gains 3 patents in China

 Xinhua, February 26, 2020 

 http://www.china.org.cn/china/2020-02/26/content_75745874.htm 


 

Antiviral drug Remdesivir gains three patents in China: official

Source: Xinhua| 2020-02-25 19:05:41|Editor: huaxia 

 http://www.xinhuanet.com/english/2020-02/25/c_138817801.htm 


 

Gilead Sciences Initiates Two Phase 3 Studies of Investigational Antiviral Remdesivir for the Treatment of COVID-19

Wed February 26, 2020 5:00 PM|Business Wire|About: GILD

-- U.S. FDA Grants Investigational New Drug Authorization to Study Remdesivir for the Treatment of COVID-19 --

FOSTER CITY, Calif.--(BUSINESS WIRE)-- Gilead Sciences, Inc. (GILD)


 https://seekingalpha.com/symbol/GILD 


 Feb 27, 2020 06:30 AMBUSINESS & TECH

China Grants Three Patents to Gilead’s Remdesivir as Hopes Rise for Effective Treatment

By Yu Dawei and Denise Jia 

 https://www.caixinglobal.com/2020-02-27/china-grants-three-patents-to-gileads-remdesivir-as-hopes-rise-for-effective-treatment-101521002.html 


 https://seekingalpha.com/pr/17792325-gilead-sciences-initiates-two-phase-3-studies-of-investigational-antiviral-remdesivir-for 


 https://www.gilead.com/purpose/advancing-global-health/covid-19 



Vir Biotechnology & WuXi Biologics Collaboration for Development of Antibodies to Treat COVID-19

Vir Biotechnology & WuXi Biologics Collaboration for Development of Antibodies to Treat COVID-19

Vir Biotechnology & WuXi Biologics Collaboration for Development of Antibodies to Treat COVID-19

 

Vir Biotechnology and WuXi Biologics Announce Collaboration for Global Development of Antibodies to Treat COVID-19

Tue February 25, 2020 8:30 AM|GlobeNewswire|About: VIR, WXXWY

SAN FRANCISCO and SHANGHAI, China, Feb. 25, 2020 (GLOBE NEWSWIRE) -- Vir Biotechnology (VIR), Inc. (Nasdaq: VIR) and WuXi Biologics (WXXWY) (stock code: 2269.HK)


 https://www.vir.bio/ 


 https://www.wuxibiologics.com/ 


 https://www.vir.bio/pipeline/#focus 


 https://seekingalpha.com/symbol/WXXWY 


 https://seekingalpha.com/symbol/VIR 


 

WUXI BIOLOGICS AND VIR BIOTECHNOLOGY ANNOUNCE COLLABORATION FOR GLOBAL DEVELOPMENT OF ANTIBODIES TO TREAT COVID-19

WuXi Biologics and Vir Biotechnology Announce Collaboration for Global Development of Antibodies to Treat COVID-19

2020/02/25

SAN FRANCISCO and SHANGHAI, February 25, 2020 – WuXi Biologics (“WuXi Bio”) (2269.HK)

 https://www.wuxibiologics.com/wuxi-biologics-vir-biotechnology-announce-collaboration-global-development-antibodies-treat-covid-19/ 

novel coronavirus (2019-nCoV) 病毒:新型冠状病毒 2019-nCoV

Coronavirus: the new disease Covid-19 explained

Could Gilead’s Sovaldi be the answer to COVID-19 coronavirus?

Iran lawmaker says 50 dead from new virus in city of Qom

image173

 

Coronavirus: the new
disease Covid-19 explained

Despite China's best efforts the coronavirus outbreak has spread rapidly around the world. Many cities in Hubei province remain in lockdown and an increasing number of international flights to China have been suspended.

BY SCMP GRAPHICS UPDATED FEBRUARY 18, 2020

 https://multimedia.scmp.com/infographics/news/china/article/3047038/wuhan-virus/index.html?src=article-launcher 


 Article Navigation >  China CDC Weekly  > 2020, 2(8): 113-122

Vital Surveillances: The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020

  • The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team

 http://weekly.chinacdc.cn/en/article/id/e53946e2-c6c4-41e9-9a9b-fea8db1a8f51 

Iran lawmaker says 50 dead from new virus in city of Qom

Could Gilead’s Sovaldi be the answer to COVID-19 coronavirus?

Iran lawmaker says 50 dead from new virus in city of Qom

 

Iran lawmaker says 50 dead from new virus in city of Qom

By AYA BATRAWYan hour ago
 DUBAI, United Arab Emirates (AP) — A staggering 50 people have died in the Iranian city of Qom from the new coronavirus this month, a lawmaker was quoted as saying on Monday, even as the Health Ministry insisted only 12 deaths have been recorded to date in the country. 

 The lawmaker said the 50 deaths date as far back as Feb. 13. Iran first officially reported cases of the virus and its first deaths in Qom on Feb. 19. 


 Feb 24, 2020 08:22 PMSOCIETY & CULTURE

Coronavirus Monday Update: China Postpones Annual Legislature Meeting as Overseas Case Numbers Rocket

 https://www.caixinglobal.com/2020-02-24/coronavirus-monday-update-china-logs-150-new-deaths-south-korea-italy-case-counts-spiral-101519489.html 


 http://china.caixin.com/2020-02-24/101519629.html 


 

Coronavirus: how Iran’s death toll came to be the highest behind only China

  • Iran’s health minister says the infections are believed to be linked to a merchant who bypassed travel restrictions by making indirect flights to China
  • Qom, south of the capital Tehran, has been identified as the centre of contagion, but authorities have warned it is possible the virus is present in all cities

John Power

Published: 8:17pm, 24 Feb, 2020

 https://www.scmp.com/week-asia/explained/article/3052143/coronavirus-how-irans-death-toll-came-be-highest-behind-only 

 

Fact Checked

How Long Will It Take to Develop a Vaccine for Coronavirus?

Share on PinterestMultiple companies are working on a vaccine to fight the new coronavirus. Getty Images

  • Several groups are working on a vaccine for the new coronavirus, but there’s no guarantee that it will be ready before the end of the current outbreak.
  • One group says they may have an experimental vaccine ready for initial testing in just a month.
  • But experts caution this expedited timeline doesn’t always allow for careful evaluation of the safety and effectiveness of the vaccines.

 https://www.healthline.com/health-news/how-long-will-it-take-to-develop-vaccine-for-coronavirus 

Could Gilead’s Sovaldi be the answer to COVID-19 coronavirus?

Could Gilead’s Sovaldi be the answer to COVID-19 coronavirus?

Could Gilead’s Sovaldi be the answer to COVID-19 coronavirus?

 

Could Gilead’s Sovaldi be the answer to COVID-19 coronavirus?

February 21, 2020

A Chinese research foundation has awarded $2.1m to four teams from Columbia University to identify antiviral drugs that work against the COVID-19 coronavirus – including a project investigating whether compounds based on Gilead’s hepatitis C drug Sovaldi could be used against the outbreak.

The funding was awarded by the Jack Ma Foundation, based in Hangzhou City, in China’s Zhejiang Province.

 https://pharmaphorum.com/news/could-gileads-sovaldi-be-the-answer-to-coronavirus/ 


 SOVALDI is sofosbuvir 

 https://www.sovaldi.com/ 

 

Early trial results from an unapproved Gilead drug, remdesivir, are expected in the next three weeks.

Results are also expected from a trial combining AbbVie’s HIV drugs lopinavir and ritonavir.


 KALETRA® (lopinavir/ritonavir) 

 https://www.kaletra.com/ 



 

7 Biotech Stocks to Buy That Could Beat the Coronavirus

Stocks fell sharply in the days following the outbreak,  

so these companies may save the day

By Chris Lau, InvestorPlace Contributor Feb 6, 2020, 10:50 am EST 

 https://investorplace.com/2020/02/7-biotech-stocks-to-buy-that-could-beat-thee companies may save the day-coronavirus/ 


 February 25, 2020 09:11 AM EST Jason Mast R&DCoronavirus

First US Covid-19 tri­als set to get un­der­way in Ne­bras­ka and Wash­ing­ton, backed by NIH

 https://endpts.com/first-us-covid-19-trials-set-to-get-underway-in-nebraska-and-washington-backed-by-nih/ 

The Bad; The Worse; The Ugly; and The Unthinkable

The Bad; The Worse; The Ugly; and The Unthinkable

Could Gilead’s Sovaldi be the answer to COVID-19 coronavirus?

image174

 

RaboResearch - Economic Research

 

Coronavirus: Outbreak of uncertainty

Special

February 14, 2020, by Michael Every et al.

 https://economics.rabobank.com/publications/2020/february/coronavirus-outbreak-of-uncertainty/ 


 

NIH Scientists Identify Atomic Structure of Novel Coronavirus Protein

NIAID Now | February 19, 2020

 https://www.niaid.nih.gov/news-events/atomic-structure-novel-coronavirus-protein 


 

CDC is closely monitoring the novel coronavirus outbreak.

Learn More

  Coronavirus Disease 2019 (COVID-19) 


 

How COVID-19 Spreads

 https://www.cdc.gov/coronavirus/2019-ncov/about/transmission.html 

mRNA-1273

The Bad; The Worse; The Ugly; and The Unthinkable

Remdesivir (GS-5734, Nuc inhibitor)

image175

 

Moderna Ships mRNA Vaccine Against Novel Coronavirus (mRNA-1273) for Phase 1 Study

Mon February 24, 2020 6:04 PM|Business Wire|About: AZN, MRK, MRNA

mRNA-1273 delivered from Company’s cGMP facility in 42 days from sequence selection

CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Moderna, Inc. (MRNA)


 

NIH Scientists Identify Atomic Structure of Novel Coronavirus Protein

NIAID Now | February 19, 2020

 https://www.niaid.nih.gov/news-events/atomic-structure-novel-coronavirus-protein 


 

Moderna Receives FDA Fast Track Designation for Zika Vaccine mRNA-1893

August 19, 2019 at 4:01 PM EDTPDF Version

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Aug. 19, 2019-- Moderna, Inc., (Nasdaq: MRNA)

 https://investors.modernatx.com/news-releases/news-release-details/moderna-receives-fda-fast-track-designation-zika-vaccine-mrna 


 https://www.modernatx.com/ 


 https://investors.modernatx.com/news-releases/news-release-details/moderna-ships-mrna-vaccine-against-novel-coronavirus-mrna-1273 


 https://www.businesswire.com/news/home/20200224005955/en/ 


 https://seekingalpha.com/symbol/MRNA 


 

Moderna, Inc. 2019 Q4 - Results - Earnings Call Presentation

Feb. 26, 2020 9:13 AM ET | About: Moderna, Inc. (MRNA) 

 https://seekingalpha.com/article/4327317-moderna-inc-2019-q4-results-earnings-call-presentation 

Remdesivir (GS-5734, Nuc inhibitor)

The Bad; The Worse; The Ugly; and The Unthinkable

Remdesivir (GS-5734, Nuc inhibitor)

 

Gilead's Remdesivir May Be Effective Against Coronavirus, WHO Says

Gilead Sciences' antiviral remdesivir may be effective against the coronavirus, the World Health Organization says.UPDATED:FEB 24, 2020 10:05 AM ESTORIGINAL:FEB 24, 2020 

 https://www.thestreet.com/investing/gilead-remdesivir-coronavirus 


 https://www.bloomberg.com/news/articles/2020-02-24/gilead-surges-after-who-comments-on-coronavirus-drug-testing?utm_medium=social&utm_content=business&utm_campaign=socialflow-organic&utm_source=twitter&cmpid=socialflow-twitter-business 


 

Gilead gains 4.8% as WHO sees potential in its antiviral drug

Feb. 24, 2020 9:57 AM ET|About: Gilead Sciences, Inc. (GILD)|By: , SA News Editor  

 https://seekingalpha.com/news/3544811-gilead-gains-4_8-who-sees-potential-in-antiviral-drug 


 https://www.gilead.com/science-and-medicine/pipeline 


 

Gilead Sciences drug remdesivir may help treat coronavirus symptoms, according to WHO


By Paul R. La Monica, CNN Business

Updated 6:04 AM ET, Tue February 25, 2020 

 https://www.cnn.com/2020/02/24/investing/gilead-sciences-coronavirus-who-remdesivir/index.html 


 February 25, 2020 09:11 AM EST Jason Mast R&DCoronavirus

First US Covid-19 tri­als set to get un­der­way in Ne­bras­ka and Wash­ing­ton, backed by NIH

 https://endpts.com/first-us-covid-19-trials-set-to-get-underway-in-nebraska-and-washington-backed-by-nih/ 

 

Adaptive COVID-19 Treatment Trial

 https://clinicaltrials.gov/ct2/show/NCT04280705?cond=covid-19&cntry=US&draw=2&rank=1 

novel coronavirus (2019-nCoV) 病毒:新型冠状病毒 2019-nCoV

from bats to pangolins to humans

The pneumonia caused by the novel coronavirus might exist for a long time, like the flu

Coronavirus traces found in recovered patients

image176

 Feb 21, 2020 06:29 AMSOCIETY & CULTURE

Coronavirus Thursday Update: Pangolin Again Linked to Coronavirus; Ministry Expects Consumer Market to Bottom Out by March

 

Thursday, Feb. 20 11:45 p.m.

Recent research again linked an endangered mammal, the pangolin, to the novel coronavirus that has sickened more than 75,000 people worldwide, as scientists strive to determine the intermediate host of the deadly virus.

 https://www.caixinglobal.com/2020-02-21/coronavirus-thursday-update-japan-reports-two-deaths-among-diamond-princess-cruise-ship-passengers-101517958.html 


 http://www.caixin.com/2020-02-20/101518165.html 


 

Wait, What’s a Pangolin?

This highly endangered and frequently trafficked creature might be the source of COVID-19.

By SHANNON PALUS FEB 19, 2020 4:52 PM 

 https://slate.com/technology/2020/02/coronavirus-origin-pangolins-trafficking-endangered.html 

Coronavirus traces found in recovered patients

The pneumonia caused by the novel coronavirus might exist for a long time, like the flu

Coronavirus traces found in recovered patients

image177

 

Coronavirus traces found in recovered patients as Hubei cases rise slightly

  • Chinese respiratory expert warns numbers could rise again as tests show people who have recovered may still be infectious
  • Globally there have been 75,773 confirmed cases and 2,129 deaths

Robert Delaney

Published: 7:21am, 21 Feb, 2020

 https://www.scmp.com/news/china/society/article/3051688/coronavirus-115-new-deaths-confirmed-hubei-officials-report-411 



The pneumonia caused by the novel coronavirus might exist for a long time, like the flu

The pneumonia caused by the novel coronavirus might exist for a long time, like the flu

The pneumonia caused by the novel coronavirus might exist for a long time, like the flu

image178

 

Coronavirus pneumonia might exist for long time, says expert

By Wang Keju | chinadaily.com.cn | Updated: 2020-02-20 11:47 

 https://www.chinadaily.com.cn/a/202002/20/WS5e4e0160a310128217278fb1.html 



There was no vaccine for Sars or Mers. Will there be one for the new coronavirus?

There was no vaccine for Sars or Mers. Will there be one for the new coronavirus?

The pneumonia caused by the novel coronavirus might exist for a long time, like the flu

 

There was no vaccine for Sars or Mers. Will there be one for the new coronavirus?

  • A month has passed since China locked down millions of people in Wuhan and other cities in Hubei at the heart of the epidemic
  • In the first part of a series, the Post looks at how the race to find a vaccine may be different than for other coronaviruses

Josephine Ma and Simone McCarthy

Published: 6:15am, 22 Feb, 2020

 https://www.scmp.com/news/china/science/article/3051853/there-was-no-vaccine-sars-or-mers-will-there-be-one-new 


 Feb 22, 2020 10:06 PMSOCIETY & CULTURE

Coronavirus Saturday Update: Global Spread Accelerates as South Korea Reports 142 New Cases; Xi Jinping Thanks Bill & Melinda Gates Foundation

 https://www.caixinglobal.com/2020-02-22/coronavirus-saturday-update-first-european-dies-in-italy-chinas-official-case-count-reaches-76392-101519032.html 

Remdesivir (GS-5734, Nuc inhibitor)

There was no vaccine for Sars or Mers. Will there be one for the new coronavirus?

Remdesivir (GS-5734, Nuc inhibitor)

 

Chinese trials for Gilead’s antiviral drug to treat coronavirus still far from reaching patient recruitment goals

  • Antiviral remdesivir is being trialled as a treatment for the novel coronavirus in 10 hospitals in Wuhan
  • Researchers have recruited more than 230 patients for the trials so far, short of the 760 targeted

Coco Feng in Beijing

Published: 7:30pm, 21 Feb, 2020

 https://www.scmp.com/tech/science-research/article/3051820/chinese-trials-gileads-antiviral-drug-treat-coronavirus-still 

 Clinical trials of an experimental antiviral drug said to “

show promise

” in treating the 

deadly coronavirus

are still far from fulfilling patient recruitment targets more than two weeks in, raising questions about whether they can be completed within previously projected timelines. 


 

  • Preliminary results from two clinical trials testing potential treatments for the COVID-19 coronavirus are expected in three weeks, WHO says.
  • One trial combines HIV drugs Lopinavir and Ritonavir, while the other is testing U.S.-based biotech Gilead Sciences’ antiviral Remdesivir.

 https://www.cnbc.com/2020/02/20/early-trial-results-for-potential-coronavirus-treatments-expected-in-three-weeks-who-says.html 


 https://www.cnbc.com/quotes/?symbol=GILD 


BiotecHeart™ - See The Light

There was no vaccine for Sars or Mers. Will there be one for the new coronavirus?

Remdesivir (GS-5734, Nuc inhibitor)

image179

  

BiotecHeart™ - See The Light

Feb. 20, 2020 10:20 AM ET

The political and socio-economic environment in America, is both depressing and disconcerting.


The hostility increases towards everyone connected with the biotech/drug industry during this highly politically charged season.


Politicos still see little to no value in biotech companies and continue to vilify them.


There continues to be much encouraging news and positive clinical tests in the biotech world, including on the coronavirus situation, for the first 2 months of 2020.

 https://seekingalpha.com/instablog/5205071-danwatson888/5411014-biotecheart-see-light 


 https://seekingbiotechalpha.com/biotecheart 


www.biotecheart.com


novel coronavirus (2019-nCoV) 病毒:新型冠状病毒 2019-nCoV

Remdesivir reduced the severity of disease, virus replication, and damage to the lungs

Remdesivir reduced the severity of disease, virus replication, and damage to the lungs

Remdesivir reduced the severity of disease, virus replication, and damage to the lungs

 Biological Sciences

RESEARCH ARTICLE

Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection

View ORCID ProfileEmmie de Wit, Friederike Feldmann, Jacqueline Cronin, Robert Jordan, Atsushi Okumura, Tina Thomas, Dana Scott, Tomas Cihlar, and Heinz FeldmannPNAS first published February 13, 2020 https://doi.org/10.1073/pnas.1922083117

  1. Edited by Michael B. A. Oldstone, Scripps Research Institute, La Jolla, CA, and approved February 7, 2020 (received for review December 16, 2019)

 Remdesivir reduced the severity of disease, virus replication, and damage to the lungs when administered either before or after animals were infected with MERS-CoV. Our data show that remdesivir is a promising antiviral treatment against MERS that could be considered for implementation in clinical trials. It may also have utility for related coronaviruses such as the novel coronavirus 2019-nCoV emerging from Wuhan, China. 


 

China’s BrightGene Manufactures APIs of Gilead’s Remdesivir

By Alex Philippidis -February 12, 2020

 Chinese drug developer BrightGene Bio-Medical Technology Co., said it has successfully manufactured the active pharmaceutical ingredients (APIs) of remdesivir (GS-5734), the Gilead Sciences antiviral candidate being tested in China human clinical trials as a treatment for 2019-nCoV novel coronavirus. [BrightGene Bio-Medical Technology]
https://www.genengnews.com/news/coronavirus-chinas-brightgene-manufactures-apis-of-gileads-remdesivir/ 


 

Chinese firm copies Gilead's remdesivir, the most promising drug against the new coronavirus

by Angus Liu | Feb 12, 2020 10:28am 

 https://www.fiercepharma.com/pharma-asia/chinese-firm-copies-gilead-s-remdesivir-most-promising-drug-against-new-coronavirus 


 BrightGene Bio-Medical Technology Co.,Ltd. 

 http://www.bright-gene.com/en/product_category.php 


 

Remdesivir (GS-5734, Nuc inhibitor)

 https://www.gilead.com/science-and-medicine/pipeline 

COVID-19 Severity of 2019-novel coronavirus (nCoV)

Remdesivir reduced the severity of disease, virus replication, and damage to the lungs

Remdesivir reduced the severity of disease, virus replication, and damage to the lungs

 

Coronavirus likely now ‘gathering steam’

 BY Alvin PowellHarvard Staff Writer

DATEFebruary 11, 2020

 In China, the number of confirmed cases of the coronavirus reached 42,700 on Feb. 11, according to the World Health Organization. To accommodate the growing number, an exhibition center was turned into a temporary hospital in Wuhan. 


 

10 February 2020 - Imperial College London‌

Report 4: Severity of 2019-novel coronavirus (nCoV)

 https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/news--wuhan-coronavirus/ 


 

Coronavirus fatality rate estimated by Imperial scientists

by Kate Wighton, Dr Sabine L. van Elsland11 February 2020

 https://www.imperial.ac.uk/news/195217/coronavirus-fatality-rate-estimated-imperial-scientists/ 


 

The Novel Coronavirus, 2019-nCoV, is Highly Contagious and More Infectious Than Initially Estimated

Steven Sanche, Yen Ting Lin, Chonggang Xu, Ethan Romero-Severson, Nick Hengartner,  View ORCID ProfileRuian Kedoi: https://doi.org/10.1101/2020.02.07.20021154 

 https://www.medrxiv.org/content/10.1101/2020.02.07.20021154v1 


 Feb 18, 2020 08:10 PMSOCIETY & CULTURE

Evidence Mounts of Japan’s Mishandling of Coronavirus Epidemic

By Dave Yin and Chen Lixiong 

 https://www.caixinglobal.com/2020-02-18/evidence-mounts-of-japans-mishandling-of-coronavirus-epidemic-101517257.htm 


 

WuXi Biologics' Subsidiary WuXi Vaccines Signed Long-Term Vaccine Manufacturing Contract with a Global Vaccine Leader

Tue February 18, 2020 5:42 AM|PR Newswire|About: WXXWY

SHANGHAI, Feb. 18, 2020 /PRNewswire/ -- WuXi Biologics (WXXWY)

 https://seekingalpha.com/pr/17781014-wuxi-biologics-subsidiary-wuxi-vaccines-signed-long-term-vaccine-manufacturing-contract 

Coronavirus outbreak

Remdesivir reduced the severity of disease, virus replication, and damage to the lungs

Remdesivir (GS-5734, Nuc inhibitor)

 Economy /  China Economy

China struggles to balance coronavirus containment with economic cost as millions return to work

  • Most Chinese companies will resume operations this week, but the coronavirus outbreak is still raging and it’s far from business as usual
  • Transport restrictions, supply chain disruptions and new workplace rules to minimise the risk of transmission all cloud the short-term economic outlook

Topic |   Coronavirus outbreak

Karen Yeung andSidney Leng

Published: 6:00am, 13 Feb, 2020

 To work or not to work – that is proving a crucial question for Chinese officials, companies and employees as the world’s second largest economy struggles to balance the risk of the deadly coronavirus with the need to resume business. 


 HEALTH

Experts envision two scenarios if the new coronavirus isn’t contained

By SHARON BEGLEY @sxbegle

FEBRUARY 4, 2020

 https://www.statnews.com/2020/02/04/two-scenarios-if-new-coronavirus-isnt-contained/ 


 

National Health Commission of the
People's Republic of China

中华人民共和国国家卫生健康委员会 

Feb 12: Daily briefing on novel coronavirus cases in China

Updated: 2020-02-12

|en.nhc.gov.cn

 http://en.nhc.gov.cn/2020-02/12/c_76463.htm 


 China / Society

Coronavirus death toll in China rises to 1,868 as epicentre reports 93 new fatalities

  • Majority of new cases and deaths have been reported from the province at the heart of the outbreak
  • China postpones annual parliamentary meeting scheduled for early March

Robert Delaney

Published: 7:02am, 18 Feb, 2020

 https://www.scmp.com/news/china/society/article/3051063/coronavirus-chinas-hubei-province-records-1807-new-cases-93 


 

The View by Mark Clifford

The coronavirus was no black swan. Hong Kong and China just weren’t ready for a crisis

  • Lessons that should have been learned after the harrowing Sars experience were not: diseases like Covid-19 will happen from time to time in a hyper-connected world, and the trust and transparency that will fortify a society’s response to such a crisis is lacking

Mark Clifford

Published: 3:00am, 19 Feb, 2020

 https://www.scmp.com/comment/opinion/article/3051079/coronavirus-was-no-black-swan-hong-kong-and-china-just-werent-ready 

Remdesivir (GS-5734, Nuc inhibitor)

World Health Organisation says it is impossible to predict the future path of the epidemic,

Remdesivir (GS-5734, Nuc inhibitor)

image180

 Actualité  Société

Nouveau coronavirus: le patient de Bordeaux a reçu du remdesivir

AFPPublié le 14/02/2020 à 14:33 | AFP 

 https://www.lepoint.fr/societe/nouveau-coronavirus-le-patient-de-bordeaux-a-recu-du-remdesivir-14-02-2020-2362739_23.php 


 Feb 16, 2020 11:16 AM

Second Batch of Experimental Gilead Coronavirus Drug Arrives in Wuhan

By Jia Tianqiong, Di Ning, Lu Yutong and Flynn Murphy 

 https://www.caixinglobal.com/2020-02-16/second-batch-of-experimental-gilead-coronavirus-drug-arrives-in-wuhan-101516104.html 

 

New drug tested in fight against coronavirus

By Liu Kun in Wuhan and Zhao Lei in Beijing | chinadaily.com.cn | Updated: 2020-02-07 23:21 

 https://www.chinadaily.com.cn/a/202002/07/WS5e3d8068a310128217275e9d.html 


chloroquine diphosphate, favipiravir and remdesivir

World Health Organisation says it is impossible to predict the future path of the epidemic,

World Health Organisation says it is impossible to predict the future path of the epidemic,

 

Drugs with potential against coronavirus in human trials

By Wang Xiaoyu  | chinadaily.com.cn | Updated: 2020-02-15 17:33 

 https://www.chinadaily.com.cn/a/202002/15/WS5e47bad4a310128217277c96.html 

 three drugs that hold great promise - chloroquine diphosphate, favipiravir and remdesivir - are undergoing human trials in the country. 


 Home / China / The fight against novel coronavirus

Latest on the novel coronavirus outbreak

chinadaily.com.cn | Updated: 2020-02-16 06:30 

 https://www.chinadaily.com.cn/a/202002/16/WS5e2a95d9a310128217273202.html 

World Health Organisation says it is impossible to predict the future path of the epidemic,

World Health Organisation says it is impossible to predict the future path of the epidemic,

World Health Organisation says it is impossible to predict the future path of the epidemic,

 

Coronavirus: China reports 105 more deaths, taking global toll to 1,775, as some cases throw 14-day incubation into doubt

  • Hubei province’s new Communist Party chief calls for less bureaucracy as number of new infections rises again
  • World Health Organisation says it is impossible to predict the future path of the epidemic, which has spread to at least 25 other countries

Cissy Zhou, Gigi Choy and Wendy Wu

Published: 7:27am, 17 Feb, 2020


 

Rethinking media coverage of COVID-19: A call to humanize people's suffering

By Hodan Osman Abdi | cgtn | Updated: 2020-02-17 11:24 

 https://global.chinadaily.com.cn/a/202002/17/WS5e4a0780a3101282172780e9.html 



novel coronavirus (2019-nCoV) 病毒:新型冠状病毒 2019-nCoV

How the death of Li Wenliang, a doctor/ordinary citizen, sparked demands for freedom of speech

How the death of Li Wenliang, a doctor/ordinary citizen, sparked demands for freedom of speech

How the death of Li Wenliang, a doctor/ordinary citizen, sparked demands for freedom of speech


Audrey Jiajia Li

Coronavirus crisis: How the death of Li Wenliang, a doctor and ordinary citizen, sparked Chinese demands for freedom of speech

  • A reluctant hero, the doctor who was reprimanded for warning about the coronavirus has, in death, become a lightning rod for public unhappiness with the government’s tight control of information

Audrey Jiajia Li

Published: 9:00am, 12 Feb, 2020

 https://www.scmp.com/comment/opinion/article/3049910/coronavirus-crisis-how-death-li-wenliang-doctor-and-ordinary 


 China / Politics

Beijing battles ‘crisis of Chernobyl proportions’ in coronavirus outbreak

  • Public fury is growing, with calls for more freedom of speech, but observers don’t expect any dramatic changes
  • Xi Jinping has been mostly absent from view, as heads start to roll in Hubei province

Jun Mai

Published: 6:00pm, 13 Feb, 2020

 https://www.scmp.com/news/china/politics/article/3050331/beijing-battles-crisis-chernobyl-proportions-coronavirus 


 

Andy Xie

How the coronavirus crisis is exposing the ills of the China model

  • An all-powerful government means a swift and effective quarantine but the same hierarchical system caused critical delays in containing the coronavirus
  • Likewise, the China model, so effective when the economy was nascent, has outlived its usefulness in a country now trying to beat the middle-income trap

Andy Xie

Published: 9:00am, 31 Jan, 2020

 https://www.scmp.com/comment/opinion/article/3048084/how-coronavirus-crisis-exposing-ills-china-model 

two monoclonal antibodies (mAbs) that bind to SARS-CoV-2 (previously known as “2019-nCoV”)

How the death of Li Wenliang, a doctor/ordinary citizen, sparked demands for freedom of speech

Coronavirus: Everything you need to know in a visual explainer = South China Morning Post

image182

 

Vir Biotechnology Identifies Two Antibodies That Bind to the Spike Protein of 2019-nCoV, Newly Named as SARS-CoV-2

Wed February 12, 2020 8:30 AM|GlobeNewswire|About: VIR 


 https://www.vir.bio/ 


 https://seekingalpha.com/symbol/VIR 


Coronavirus: Everything you need to know in a visual explainer = South China Morning Post

Coronavirus: Everything you need to know in a visual explainer = South China Morning Post

Coronavirus: Everything you need to know in a visual explainer = South China Morning Post

 

South China Morning Post 

Coronavirus: Everything you need to know in a visual explainer

The coronavirus which was first reported in Wuhan late last year has quickly spread around the world. The Chinese authorities have locked down many cities in China's Hubei province, and some international flights to China have been suspended.

BY SCMP GRAPHICS UPDATED FEBRUARY 11, 2020

 https://multimedia.scmp.com/infographics/news/china/article/3047038/wuhan-virus/index.html 


 Feb 13, 2020 12:53 PMSOCIETY & CULTURE

Coronavirus Latest: Wuhan Infections Jump By More Than 13,000, Hubei Party Chief Removed

 https://www.caixinglobal.com/2020-02-13/coronavirus-latest-since-feb-1-confirmed-cases-14380-in-china-canada-starts-limited-evacuation-but-no-travel-ban-101510591.html 


 FEBRUARY 13, 2020 / 12:24 AM / UPDATED AN HOUR AGO

Factbox: Latest on coronavirus spreading in China and beyond

 (Reuters) - Here are the latest developments around the coronavirus outbreak: 

 https://www.reuters.com/article/us-china-health-latest-idUSKBN2070F2?taid=5e45317781f80800015293c5&utm_campaign=trueAnthem:+Trending+Content&utm_medium=trueAnthem&utm_source=twitter 

Remdesivir

Coronavirus: Everything you need to know in a visual explainer = South China Morning Post

Johnson & Johnson Launches Multi-Pronged Response to Coronavirus Global Public Health Threat

image183

 

Gilead Sciences Statement on the Company’s Ongoing Response to the 2019 Novel Coronavirus (2019-nCoV)

Foster City, Calif., January 31, 2020 


 Remdesivir has demonstrated in vitro and in vivo activity in animal models against the viral pathogens MERS and SARS, which are coronaviruses that are structurally similar to 2019-nCoV. 


 

Coronavirus-Drug Development Becomes a Top Focus at Gilead

Drugmaker sprints to build up capacity to produce its promising antiviral remdesivir should it prove effective in studies in China

 https://www.wsj.com/articles/gilead-sciences-scrambles-to-supply-experimental-coronavirus-drug-11581522704 


 

A Chinese Drugmaker Has Started Mass-Producing an Experimental Drug for COVID-19

 Suzhou-based BrightGene Bio-Medical Technology 

 https://time.com/5782633/covid-19-drug-remdesivir-china/ 


 BrightGene Bio-Medical Technology Co. Ltd. (Suzhou, China)  

 http://www.bright-gene.com/en/ 


 

Chinese firm copycats Gilead's remdesivir, the most promising drug against the new coronavirus

by Angus Liu | Feb 12, 2020 10:28am 

 https://www.fiercepharma.com/pharma-asia/chinese-firm-copies-gilead-s-remdesivir-most-promising-drug-against-new-coronavirus 


 

BrightGene Bio-Medical Technology Co Ltd

COMPANY INFO 

 https://www.bloomberg.com/quote/688166:CH 

 

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

Cell Research (2020)

 https://www.nature.com/articles/s41422-020-0282-0 

Johnson & Johnson Launches Multi-Pronged Response to Coronavirus Global Public Health Threat

Coronavirus: Everything you need to know in a visual explainer = South China Morning Post

Johnson & Johnson Launches Multi-Pronged Response to Coronavirus Global Public Health Threat

image184


Johnson & Johnson Announces Collaboration with U.S. Department of Health & Human Services to Accelerate Development of a Potential Novel Coronavirus Vaccine

Tue February 11, 2020 4:30 PM|PR Newswire|About: JNJPR Newswire

NEW BRUNSWICK, N.J., Feb. 11, 2020 /PRNewswire/ -- Johnson & Johnson (JNJ)


 

Johnson & Johnson Launches Multi-Pronged Response to Coronavirus Global Public Health Threat

Initiating Vaccine Development and Providing Supplies of Antiviral Medicines to China for Investigational Use

 https://www.jnj.com/johnson-johnson-launches-multi-pronged-response-to-coronavirus-global-public-health-threat 


 Johnson & Johnson Announces Collaboration with U.S. Department of Health and Human Services to Fight InfluenzaJanssen and Biomedical Advanced Research and Development Authority (BARDA) join forces to accelerate new therapies and vaccines to protect communities against the threat of a pandemic

NEW BRUNSWICK, N.J., – September 15, 2017 – Johnson & Johnson (NYSE: JNJ)

 https://www.jnj.com/media-center/press-releases/johnson-johnson-announces-collaboration-with-us-department-of-health-and-human-services-to-fight-influenza 


 https://www.jnj.com/johnson-johnson-announces-donation-of-up-to-500-000-regimens-of-janssens-investigational-ebola-vaccine-to-support-outbreak-response-in-democratic-republic-of-the-congo-drc 



 https://www.jnj.com/coronavirus 


 

What You Need to Know About the Latest on the Coronavirus—and a Potential Preventive Vaccine

The coronavirus has made headlines as it has spread from China to other parts of the world. To help stop the global outbreak in its tracks, Johnson & Johnson is already hard at work on a potential preventive vaccine.By Johnson & JohnsonJanuary 28, 2020 

 https://www.jnj.com/latest-news/what-you-need-to-know-about-coronavirus-and-a-potential-johnson-johnson-vaccine 


 https://www.janssen.com/ 


 https://www.jnj.com/innovation 



novel coronavirus (2019-nCoV) 病毒:新型冠状病毒 2019-nCoV

Remdesivir (GS-5734, Nuc inhibitor)

Arbidol and Darunavir, could effectively inhibit replication of the new strain

Arbidol and Darunavir, could effectively inhibit replication of the new strain

 

US drug cleared for trials in Wuhan

By Liu Zhihua | China Daily | Updated: 2020-02-05 09:07 

 http://www.chinadaily.com.cn/a/202002/05/WS5e3a156ca310128217274f36.html 


 

Antiviral drug Remdesivir arrives in China for clinical trial: official

Source: Xinhua| 2020-02-04 23:47:08|Editor: Mu Xuequan 

 http://www.xinhuanet.com/english/2020-02/04/c_138755837.htm 


 Prognosis

Trials of Gilead Coronavirus Drug in China Could Start Next Week

By February 4, 2020, 3:44 PM EST 

 https://www.bloomberg.com/news/articles/2020-02-04/trials-of-gilead-coronavirus-drug-in-china-could-start-next-week 


 Remdesivir is being rushed into trials for the new virus because it previously showed promise in laboratory tests against SARS, a virus similar to the current coronavirus. It’s already been used on the first U.S. coronavirus patient in Washington state, who improved after getting the drug, as well as a handful of other coronavirus patients in the West. 

 

China Wants to Patent Gilead’s Experimental Coronavirus Drug

Bloomberg NewsFebruary 5, 2020, 12:00 AM EST Updated on February 5, 2020, 6:47 AM EST

  • Wuhan’s virology institute has applied for remdesivir’s patent
  • Gilead said human trials on the drug have begun in China

 https://www.bloomberg.com/news/articles/2020-02-05/china-is-trying-to-patent-gilead-s-experimental-coronavirus-drug 


 

 

Cell Research

ISSN 1748-7838 (online) 

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

 https://www.nature.com/articles/s41422-020-0282-0 


 

Experimental drug offers silver lining

By ZHANG ZHIHAO | China Daily | Updated: 2020-02-06 11:15

Clinical trials begin for remdesivir, which has shown promise in studies

 https://www.chinadaily.com.cn/a/202002/06/WS5e3b84d5a310128217275700.html 

Arbidol and Darunavir, could effectively inhibit replication of the new strain

Arbidol and Darunavir, could effectively inhibit replication of the new strain

Arbidol and Darunavir, could effectively inhibit replication of the new strain

image185

 China / Society

China’s health officials say priority is to stop mild coronavirus cases from getting worse

  • National Health Commission admits Wuhan lacked intensive care facilities at start of the outbreak, but more beds and staff have now been provided
  • And an epidemiologist says preliminary tests have shown two drugs, Arbidol and Darunavir, could effectively inhibit replication of the new strain

William Zheng andMimi Lau

Published: 11:46pm, 4 Feb, 2020

 https://www.scmp.com/news/china/society/article/3048993/chinese-officials-say-priority-stop-mild-coronavirus-cases 


 Arbidol, commonly available as Umifenovir, is a potent antiviral used to treat and prevent influenza, while Darunavir is used to treat and prevent HIV/Aids. 


 

Umifenovir in treatment of influenza and acute respiratory viral infections in outpatient care

 https://www.ijidonline.com/article/S1201-9712(18)34836-7/fulltext 


 PREZISTA® (darunavir) is a prescription HIV-1 (Human Immunodeficiency Virus type-1) medicine used with NORVIR® (ritonavir) and other antiretroviral medicines to treat HIV-1 infection in adults. HIV is the virus that causes AIDS (Acquired Immune Deficiency Syndrome). 

 https://www.prezista.com/ 


 

PREZISTA® (darunavir) is a prescription HIV‑1 (Human Immunodeficiency Virus type‑1) medicine used with NORVIR® (ritonavir) and other antiretroviral medicines to treat HIV-1 infection in adults. HIV is the virus that causes AIDS (Acquired Immune Deficiency Syndrome).

PREZISTA® should not be used in children under 3 years of age.

When used with other antiretroviral medicines to treat HIV‑1 infection, PREZISTA® may help:

  • reduce the amount of HIV-1 in your blood. This is called "viral load."
  • increase the number of CD4+ (T) cells in your blood that help fight off other infections.

PREZISTA® is always taken with and at the same time as NORVIR® (ritonavir) in combination with other HIV‑1 medicines for the treatment of HIV‑1 infection in adults. PREZISTA® should also be taken with food. 

 https://www.janssencarepath.com/patient/prezista/cost-support 


NORVIR® (ritonavir) tablets and oral solution are prescription medicines each used with other antiviral medicines to treat people with human immunodeficiency virus (HIV-1) infection.

NORVIR® (ritonavir) oral powder is a prescription medicine that is used with other antiviral medicines to treat children with HIV-1 infection.

HIV-1 is the virus that causes AIDS (Acquired Immune Deficiency Syndrome).

 https://www.norvir.com/?cid=ppc_ppd_norvir_ggl_br_0017 


Remdesivir (GS-5734, Nuc inhibitor)

Arbidol and Darunavir, could effectively inhibit replication of the new strain

Life and Death in a Wuhan Coronavirus ICU


 https://www.scmp.com/business/article/3049227/who-owns-magic-cure-chinas-move-patent-gileads-experimental-drug-could  

China wants to patent Gilead's experimental coronavirus drug

 BEIJING (BLOOMBERG) - Chinese researchers have applied for a local patent on an experimental Gilead Sciences drug that they believe might fight the novel coronavirus

 https://www.straitstimes.com/asia/east-asia/coronavirus-china-wants-to-patent-gileads-experimental-wuhan-virus-drug?utm_medium=Social&utm_campaign=STFB&utm_source=Facebook#Echobox=1580898360 


 https://www.straitstimes.com/wuhan-virus-outbreak 


 FEBRUARY 5, 2020 / 2:21 AM / UPDATED 11 HOURS AGO

China lab seeks patent on use of Gilead's coronavirus treatment

Zhang Yan, David Stanway

BEIJING/SHANGHAI (Reuters)

 “Even if the Wuhan Institute’s application gets authorized, the role is very limited because Gilead still owns the fundamental patent of the drug,” said Zhao Youbin, a Shanghai-based intellectual property counsel at Purplevine IP Service Co. 

 https://www.reuters.com/article/us-china-health-patent-idUSKBN1ZZ0RL 

 

Remdesivir (GS-5734, Nuc inhibitor)

Potential Indication: Ebola Virus Infection

PHASE 2
https://www.gilead.com/science-and-medicine/pipeline 


 Feb 06, 2020 03:35 AMBUSINESS & TECH

China Wants to Patent Gilead’s Experimental Coronavirus Drug

 https://www.caixinglobal.com/2020-02-06/china-wants-to-patent-gileads-experimental-coronavirus-drug-101512006.html 


 

Who owns the coronavirus cure? China’s move to patent Gilead’s experimental drug for the novel virus could lead to legal wrangle

  • Institute of Virology in Wuhan, the epicentre of the global coronavirus outbreak, filed a patent for Gilead’s remdesivir antiviral drug on January 21
  • In a statement to the Post, California-based Gilead said it applied for a global patent in 2016, including in China, for using the drug to treat all coronavirus-linked illnesses

Eric Ng

Published: 8:00am, 6 Feb, 2020

 “We are aware of reports of the Wuhan Institute for Virology’s patent application,” said Sonia Choi, Gilead’s vice president of public affairs in a telephone interview with South China Morning Post. “Our focus at this time is on rapidly determining the potential for remdesivir as a treatment for [the novel coronavirus] and accelerating manufacturing in anticipation of potential future supply needs.” 

 “In theory, a patent owner may be able to use its patent to stop other companies from manufacturing, importing or selling that drug in China,” he said. “But a patent cannot stop doctors from prescribing the drug to treat a patient.” 

 https://www.scmp.com/business/article/3049227/who-owns-magic-cure-chinas-move-patent-gileads-experimental-drug-could 

Life and Death in a Wuhan Coronavirus ICU

mRNA-1273 to prevent novel coronavirus (2019-nCoV) disease, in collaboration with the NIH

Life and Death in a Wuhan Coronavirus ICU

 


 Feb 06, 2020 07:40 AMSOCIETY & CULTURE

Reporter’s Notebook: Life and Death in a Wuhan Coronavirus ICU

By Xiao Hui 

 Translated By Sun Huixia and Dave Yin