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IDA Ireland

Operations in Ireland

 Pfizer has IDA-supported facilities at five sites in Ireland that employ 3,500 people. It is the largest pharmaceutical sector investor and employer. From an initial investment of €10 million in 1969, Pfizer's total investment in Ireland now stands at nearly €8 billion.  

 https://www.idaireland.com/how-we-help/case-studies/pfizer 


 GSK employs 1,450 people in Ireland and first established operations here in 1975. It has two manufacturing operations in Dungarvan and is the largest employer in the town with almost 700 staff; it has a third manufacturing operation, where it develops and produces a range of bulk pharmaceuticals, together with R&D and European Trading operations in Cork; and in Dublin there are Sales and Marketing functions. 

 https://www.idaireland.com/how-we-help/case-studies/gsk 


 In 1997, Takeda, the largest pharmaceutical company in Japan, established a Formulation Plant in Bray, Wicklow, for the manufacture of three of the company’s blockbuster drugs (Prevacid, Blopress and Actos). The establishment of this facility was paramount to Takeda’s strategy in responding to expanding growth in the European and US markets. This plant has significantly expanded its operation since inception and operates on a 24 hour/7 day basis. 

 https://www.idaireland.com/how-we-help/case-studies/takeda 

Company Overview

 Merck & Co., New Jersey is a global research-driven pharmaceutical company and is the fifth largest pharmaceutical company in the world. Outside North America it is known as MSD. 

MSD has 5 facilities supported by IDA with over 1,900 permanent jobs. It has invested over €2.2 billion in Ireland. It procures significant amounts of Irish-sourced raw materials and services.
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BiotechVortex™

 

A BIOTECH VORTEX™ is occurring across the entire healthcare sector as companies are now Seeking Biotech Partnerships to gain momentum.


Biotech & Biotech Partnerships.


Biotech & Medtech Partnerships.


Biotech & Medtech & Medical 

Universities Partnerships.


Biotech & Health Systems Partnerships.

 

BiotechVortex™

Innovation-Lounge with focus on diabetes

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 Lilly Germany kicks off Innovation-Lounge with focus on diabetes

by LillyPad 30/07/2019 

 By Dr. Stefanie Beck, Government Affairs Manager Lilly Germany. 

Lilly current products include: By Therapeutic

iPhone, Apple Watch, iPad and the Beddit sleep monitoring device, in combination with digital apps

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  • LILLY, EVIDATION HEALTH AND APPLE STUDY SHOWS PERSONAL DIGITAL DEVICES MAY HELP IN THE IDENTIFICATION OF MILD COGNITIVE IMPAIRMENT AND MILD ALZHEIMER'S DISEASE DEMENTIA

Lilly, Evidation Health and Apple Study Shows Personal Digital Devices May Help in the Identification of Mild Cognitive Impairment and Mild Alzheimer's Disease Dementia

08/08/2019Download PDF

INDIANAPOLIS, Aug. 8, 2019 /PRNewswire/ -- Initial results from a feasibility study conducted by Eli Lilly and Company (NYSE: LLY), Evidation Health, and Apple Inc. (NASDAQ: AAPL)


 https://seekingalpha.com/pr/17597726-lilly-evidation-health-apple-study-shows-personal-digital-devices-may-help-identification 

New ways to measure health in everyday life.

Optune® Tumor Treating Fields

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China National Medical Products Administration Grants Innovative Medical Device Designation for Optune® in China

Mon August 12, 2019 7:30 AM|Business Wire|About: NVCR, ZLAB

SHANGHAI & ST. HELIER, Jersey--(BUSINESS WIRE)-- Zai Lab Limited (ZLAB), a Shanghai-based innovative commercial stage biopharmaceutical company, and Novocure (NVCR),


 http://www.zailaboratory.com/products/index.aspx 

Optune is a noninvasive, portable device that is classified as durable medical equipment (DME).

Financial Time - Novartis (NVS) to file 50 applications for drug approvals in China by 2023

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Novartis bets big on China, 50 new drug applications expected by 2023

Aug. 12, 2019 9:36 AM ET|About: Novartis AG (NVS)|By: , SA News Editor  

FT article link

Insulet Corporation (PODD)

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Insulet Omnipod DASH™ System Mobile Apps Now Available for iOS Devices

Fri August 9, 2019 10:05 AM|Business Wire|About: PODD 

OMNIPOD DASH™ SYSTEM NOW WITH APPS!

Biktarvy® (Bictegravir, Emtricitabine and Tenofovir Alafenamide)

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China National Medical Products Administration Approves Biktarvy® (Bictegravir, Emtricitabine and Tenofovir Alafenamide) for Treatment of HIV-1 Infection

Fri August 9, 2019 8:30 AM|Business Wire|About: GILD

-- Biktarvy demonstrated high efficacy and a high barrier to resistance in clinical trials through 48 weeks --

FOSTER CITY, Calif.--(BUSINESS WIRE)-- Gilead Sciences, Inc. (GILD

 

Québec Provides Access to Biktarvy® for the Treatment of HIV

Thu August 15, 2019 8:00 AM|Canada Newswire|About: GILD 

 MISSISSAUGA, ON, Aug. 15, 2019 /CNW/ - Gilead Sciences Canada, Inc. (Gilead Canada) 

 https://seekingalpha.com/pr/17604746-quebec-provides-access-biktarvy-treatment-hiv 

BIKTARVY is a complete, 1-pill, once-a-day prescription medicine used to treat HIV-1 in adults. It can either be used in people who have never taken HIV-1 medicines before, or people who are replacing their current HIV-1 medicines and whose healthcare provider determines they meet certain requirements. BIKTARVY does not cure HIV-1 or AIDS. HIV-1 is the virus that causes AIDS.
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I-Mab Biopharma Co.

Chinese Drug Developer I-Mab Is Said to File for U.S. IPO By Bloomberg / Aug 03, 2019 02:15 AM / Bus

 

In-licensing: through in-licensing partnerships with global biotech partners, including MorphoSys, Genexine, MacroGenics and Ferring, we have quickly built our China Portfolio by acquiring multiple innovative clinical stage assets with favorable clinical safety and early efficacy data. In that respect, we are often considered an ideal China partner by our global partners because of our strong development capabilities and proven track record.

Out-licensing: the out-licensing deals enable us to streamline our pipeline and focus our resources on the most valuable assets. In addition, we seek co-development opportunities to share development costs and risks and territorial commercial rights with our partners. In the past two years, we have out-licensed three de-prioritized assets and initiated four co-development programs with partners such as ABL Bio, Everest Medicines and WuXi Biologics. The revenue we generated from out-licensing and co-development deals is expected to continue to grow as our pipeline progresses.


 

R&D Site in Shanghai

 Our headquarters is based in Zhangjiang, Pudong, Shanghai. The Shanghai site has a state-of-the-art laboratory facility that hosts both our discovery unit and the CMC research unit (cell line and analytical development). There are also large open-office spaces hosting the R&D organization, the CMC department and the operation teams. Site address: Suites 802, 505, 702, West Tower, 88 Shangke Road, Pudong New District, Shanghai, China. 

 http://www.i-mabbiopharma.com/en/Facilities.html 


 Copyright I-MAB Biopharma Co., Ltd. all rights reserved 2019 

I-Mab Biopharma Co.

 

China Portfolio

Pipeline Strategy and Progress
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Swiss Biotech Association

Global Innovation Index 2019: Switzerland is the world’s most-innovative country

 

  • Wednesday, July 24, 2019 @ 12:00 am

Switzerland is the world’s most-innovative country followed by Sweden, the United States of America (U.S.), the Netherlands and the United Kingdom (U.K.), according to the 2019 edition of the Global Innovation Index (GII), which also identifies regional leaders India, South Africa, Chile, Israel and Singapore, with China, Vietnam and Rwanda topping their income groups.


 Switzerland is the world’s most innovative country followed by Sweden, the United States of America (U.S.), the Netherlands and the United Kingdom (U.K.), according to the GII 2019.   https://www.wipo.int/global_innovation_index/en/2019/index.html  

Swiss Biotech Association

 

Contact

Swiss Biotech Association
Stauffacherstrasse 16
8004 Zürich
T: +41 44 455 56 78
E-mail

Recently updated member listings
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Varian (VSEA) (NYSE: VAR)

HDR Brachytherapy Cancer Treatments with Varian Bravos Afterloader System

 Karolinska University Hospital Solna Delivers HDR Brachytherapy Cancer Treatments with Varian Bravos Afterloader System

Thu July 25, 2019 3:00 AM|PR Newswire|About: VAR 

 

NEWS PROVIDED BY Varian   Jul 25, 2019, 03:00 ET


 PALO ALTO, Calif. and STOCKHOLM, July 25, 2019 /PRNewswire/ -- Varian (NYSE: VAR) announced that the Karolinska University Hospital Solna in Sweden is the first hospital in Scandinavia to deliver High Dose Rate (HDR) brachytherapy treatments using the new Bravos™ afterloader system 


  http://www.varian.com  


 https://seekingalpha.com/article/4277633-varian-medical-systems-inc-2019-q2-results-earnings-call-slides 


 https://www.varian.com/oncology/products/treatment-delivery/brachytherapy-afterloaders-applicators/bravos 


 https://www.prnewswire.com/news-releases/karolinska-university-hospital-solna-delivers-hdr-brachytherapy-cancer-treatments-with-varian-bravos-afterloader-system-300889555.html 


Karolinska University Hospital

 Karolinska University Hospital is one of Europe’s premier health facilities. Together with the world-respected Karolinska Institutet, we lead in development and medical break-throughs.  

 https://www.karolinska.se/?splitoption=splitdecision 

Karolinska University Hospital
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Seoul Innovation QuickFire Challenge: Smart Healthcare

The Challenge - Johnson & Johnson Innovation - JLABS (JLABS) in collaboration with Seoul Metropolitan Government (SMG), Korea Health Industry Development Institute (KHIDI), Janssen Korea Ltd.


 

The Challenge 

In 2018, the Asia-Pacific health tech industry had a record-breaking year in total funding, closing at $6.3 billion, making the Asia-Pacific health tech ecosystem the second largest in the world in value, behind only the United States[1]. As the health tech boom surges in the Asia-Pacific, healthcare solutions geared towards medical diagnosis, health management, patient solutions, and population health management garnered multimillion-dollar deals.

Health tech may hold the promise of providing new inroads for the biggest healthcare challenges of our time. From patient care, to data management, personalized medicine and population health, Smart Healthcare tools including blockchain, AI, 3D printing, and wearables, may be the key that unlocks new advances that make a meaningful difference for people around the globe.

That’s why Johnson & Johnson Innovation - JLABS (JLABS) in collaboration with Seoul Metropolitan Government (SMG), Korea Health Industry Development Institute (KHIDI), Janssen Korea Ltd. are launching the Seoul Innovation QuickFire Challenge in Smart Healthcare. Up to two innovators with the best idea, technology, or solution that aims to address a health need for the world's population will receive up to KRW150,000,000 (approximately US$134,000) in grant funding, entrance to the Seoul Bio Hub, and mentorship from experts at the Johnson & Johnson Family of Companies.

Seoul Innovation QuickFire Challenge in Smart Healthcare.

 Awards

Up to KRW 150,000,000 (~ US $134,000)

  • One-year residency at the Seoul Bio Hub
  • A year of mentorship and coaching from experts in science and commercialization at the Johnson & Johnson Family of Companies
  • Access to the Johnson & Johnson Innovation – JLABS ecosystem

Seoul Innovation QuickFire Challenge
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JLABS @ Shanghai

SHANGHAI, June 27, 2019

 

The world’s largest JLABS and the first in Asia Pacific aims to support more than 50 life science start-ups from around the world with the hope to accelerate healthcare innovation in China and globally

SHANGHAI, June 27, 2019 — Johnson & Johnson Innovation, Division of Johnson & Johnson (China) Investment Ltd.

Johnson & Johnson Innovation Opens JLABS @ Shanghai in Collaboration with Shanghai Pharma Engine Company Ltd. July 3, 2019 -

seeking biotech alpha partnerships

Bristol-Myers Squibb & Tsinghua University

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 Bristol-Myers Squibb and Tsinghua University Announce Collaboration to Accelerate Early Research into Potential Therapies for Autoimmune Diseases and Cancer 

BMY & Tsinghau

Abbvie & Rice University

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 AbbVie and Rice University establish K.C. Nicolaou Research Accelerator to advance therapies in oncology 

ABBV & RICE

Johnson & Johnson & Boston University

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Johnson & Johnson and Boston University Announce a New Alliance Focused on Tackling Lung Cancer 

JNJ & BU

Amgen And Cedars-Sinai

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Amgen And Cedars-Sinai Partner For Improved Healthcare Quality

Thu July 19, 2018 4:00 PM|PR Newswire|About: AMGN 

AMGN & Cedars-Sinai

jlabs-shanghai

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Shanghai Lung Cancer Innovation QuickFire Challenge

JLABS

Biotech & University Partnerships

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 "partnerships help foster a culture of entrepreneurship and innovation in the university community.”. 

Biotech & university partnerships

seeking biotech alpha updates

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 Bill Nygren Comments on Bristol-Myers Squibb = "The company’s two most valuable drugs Opdivo and Yervoy should continue to grow revenue as they maintain effectiveness with new tumor types. Bristol Myers Squibb also has the most new molecular agents and the highest number of combinations of agents in trials. Moreover, the company’s R&D and marketing prowess also make it a desired partner for promising academic and small biotech innovators. 

Bill Nygren on BMY
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 Bill Nygren - Oakmark Fund manager -  invested in 6.5 million shares of Bristol-Myers Squibb for an average price of $54.03 per share. The manager dedicated 1.85% of his equity portfolio to the position. 

​Ray Dalio - Bridgewater Associates also invested in Bristol-Myers during the quarter.

Bill Nygren - Oakmark Fund Manager
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 U.S. Food and Drug Administration Accepts for Priority Review Bristol-Myers Squibb’s Application for Empliciti (elotuzumab) Plus Pomalidomide and Low-Dose Dexamethasone in Patients with Relapsed or Refractory Multiple Myeloma

Empliciti
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 Jeff Auxier comments on Merck = Merck beat estimates in the second quarter of 2018 with $10.5 billion in revenues and EPS of $1.06. They were buoyed in the quarter by their signature cancer drug KEYTRUDA which allows the body’s immune system to destroy cancerous cells by blocking a protective enzyme in cancer cells. Sales grew 89% in the quarter to $1.667 billion and are expected to continue to grow to upwards of $13 billion annually by 2026. Recently KEYTRUDA was approved in China and the EU for metastatic melanoma. 

Jeff Auxier on MRK - Auxier Asset Management
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Jeff Auxier Comments on Biogen = Biogen saw revenues increase by 9% to $3.4 billion. Revenue growth was driven by Spinal Muscular Atrophy drug Spinraza which saw a 108% increase in revenue. Spinraza is Biogen’s fastest growing drug which they hope will be able to offset the slowing Multiple Sclerosis product line. Biogen presented the detailed results for the phase II trials of their Alzheimer’s drug BAN2401 on July 25th. The results of the trial were positive with tested patients showing 30% less cognitive decline over 18 months than those who received the placebo, but the presentation garnered a mixed reception and caused Biogen’s stock to fall 9% in after-hours trading. Earlier in July, Biogen announced that the trials of the drug were looking very positive without giving any details, and this announcement may have caused many to anticipate that the results would be better than what was ultimately shown. Currently, Biogen’s stock is hurting from the results announcement, but their outlook is still positive in the long-run due to the strength of their pipeline. Another Alzheimer’s drug in Biogen’s pipeline, Aducanumab, just finished its enrollment for two phase III trials. This drug has been regarded as more promising than BAN2401, and if it is successful Biogen will have the only drug in a $12 billion market.
 

Jeff Auxier on BIIB - Auxier Asset Management
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  PR Newswire

THOUSAND OAKS, Calif., July 31, 2018 /PRNewswire/ -Amgen (AMGN) announced the groundbreaking of its new next-generation biomanufacturing plant that will be constructed at its West Greenwich, R.I. campus. The new plant is the first-of-its-kind in the U.S. and will use Amgen's proven next-generation biomanufacturing capabilities to manufacture products for the U.S.and global markets. 

Amgen Breaks Ground On Next-Generation Biomanufacturing Plant In Rhode Island

seeking biotech alpha selected investments

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 European Commission Approves BLINCYTO® (blinatumomab) For Use In Pediatric Patients With Philadelphia Chromosome-Negative Relapsed Or Refractory B-Cell Precursor Acute Lymphoblastic Leukemia 

Blincyto®
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 AbbVie Receives U.S. FDA Approval of ORILISSA™ (elagolix) for the Management of Moderate to Severe Pain Associated with Endometriosis

orilissa™
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 Merck Obtains Earlier FDA Approval For Expanded Label Of Keytruda In Front-Line Lung Cancer

Keytruda®
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 First-ever Study of Lilly's Humulin® R U-500 Administered in an Insulin Pump Shows Improved A1C in People with Type 2 Diabetes 

Humulin® R U 500
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U.S. FDA Approves XTANDI® (enzalutamide) for the Treatment of Men with Non-Metastatic Castration-Resistant Prostate Cancer (CRPC). XTANDI is now approved to treat another form of advanced prostate cancer. XTANDI is now approved to treat men with prostate cancer that no longer responds to treatment that lowers testosterone and has not spread to other parts of the body.


xtandi®
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 New Real-World Study Finds Long-Term XARELTO® (rivaroxaban) Use Resulted in Fewer Strokes and Systemic Emboli Compared to Warfarin in Frail Patients with Non-Valvular Atrial Fibrillation 

Xarelto®

seeking biotech alpha selected investments

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 Lynparza significantly delays disease progression in Phase III 1st-line SOLO-1 trial for ovarian cancer 

lynparza®
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 Abiomed Announces Approval in India for the Impella 2.5®, Impella CP® and Impella 5.0® Heart Pumps and First Indian Patient Treated 

Impella 2.5®, Impella CP®, Implella 5.0®
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Bristol-Myers Squibb’s Opdivo® (nivolumab) + Low-Dose Yervoy® (ipilimumab) is the First Immuno-Oncology Combination Approved for MSI-H/dMMR mCRC Patients Who Progressed Following Treatment with a Fluoropyrimidine, Oxaliplatin and...

Opdivo® + YERVOY®
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 Novartis Kisqali® now first and only CDK4/6 inhibitor that is indicated with fulvestrant as both initial or second-line treatment for postmenopausal women with HR+/HER2- advanced breast cancer 

kisqali®
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 BIOGEN AND EISAI REPORT DATA FROM LONG-TERM EXTENSION PHASE 1B STUDY OF INVESTIGATIONAL ALZHEIMER’S DISEASE TREATMENT ADUCANUMAB 

aducanumab
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 Study Shows Improved Quality of Life and Reduced Symptoms In Patients Treated with Medtronic Cryoballoon 

Medtronic Arctic Front Advance™ Cryoballoon

seeking biotech alpha selected investments

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 Gilead and Galapagos Announce TORTUGA Phase 2 Study of Filgotinib in Ankylosing Spondylitis Achieves Primary Endpoint 

Filgotinib
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 Intuitive Submits New Robotic-Assisted Platform to FDA for Obtaining Lung Biopsies

robotic-assisted platform
Illumina Receives Approval of MiSeq™Dx System in China

 Illumina Receives Approval of MiSeq™Dx System in China

MiSeq™ DX System
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 FDA Grants Breakthrough Therapy Designation for Genentech’s TECENTRIQ in Combination With Avastin as First-Line Treatment for Advanced or Metastatic Hepatocellular Carcinoma (HCC) 

TECENTRIQ®
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 FDA APPROVES EYLEA® (AFLIBERCEPT) INJECTION SBLA IN WET AGE-RELATED MACULAR DEGENERATION 

Eylea®
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 Celgene Announces Phase III ‘AUGMENT' Study of REVLIMID® in Combination with Rituximab (R²) for the Treatment of Patients with Relapsed/Refractory Indolent Lymphoma Met Primary Endpoint

Revlimid®

seeking biotech alpha selected investments

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 Abbott Receives FDA Approval for Next-Generation MitraClip® Device to Treat People with Leaky Heart Valves 

MitraClip®
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 Adults with type 2 diabetes treated with Tresiba® (insulin degludec injection) had a significant reduction in A1C and a 30% lower rate of hypoglycaemic episodes after starting basal insulin 

Tresiba®
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 Neurocrine Biosciences is a San Diego based biotechnology company focused on neurologic and endocrine related disorders. The Company’s three late-stage clinical programs are: elagolix, a gonadotropin-releasing hormone antagonist for women’s health that is partnered with AbbVie Inc.; opicapone, a novel, once-daily, peripherally-acting, highly-selective catechol-o-methyltransferase inhibitor under investigation as adjunct therapy to levodopa in Parkinson’s patients; and INGREZZA™ (valbenazine), a novel, once-daily, selective VMAT2 inhibitor under investigation for the treatment of Tourette Syndrome. INGREZZA (valbenazine) capsules was approved by the FDA on April 11, 2017 for the treatment of adults with tardive dyskinesia and is currently commercialized by Neurocrine in the United States. 

NORTH CHICAGO, Ill., Aug. 22, 2018 /PRNewswire/ -- AbbVie (NYSE: ABBV), a research-based global biopharmaceutical company, in cooperation with Neurocrine Biosciences, Inc. (NASDAQ: NBIX),
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 Sangamo Announces 16 Week Clinical Results Including Reductions In Glycosaminoglycans In Phase 1/2 Trial Evaluating SB-913, A Zinc Finger Nuclease Genome Editing Treatment For MPS II (Hunter Syndrome)

Zinc Finger Nuclease Genome Editing Treatment
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 FDA Approves ORKAMBI® (lumacaftor/ivacaftor) as First Medicine to Treat the Underlying Cause of Cystic Fibrosis for Children Ages 2-5 Years with Most Common Form of the Dise 

Orkambi®
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 BioMarin Doses First Participant in Phase 2 Study of Vosoritide for Treatment of Infants and Young Children with Achondroplasia

Vosoritide

seeking biotech alpha selected investments

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 BeiGene Initiates New Phase 3 Trial of Anti-PD-1 Antibody Tislelizumab Combined with Chemotherapy as First-line Treatment for Patients with Advanced Squamous Non-Small Cell Lung Cancer in China

Tislelizumab
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PerkinElmer’s EUROIMMUN Receives FDA Clearance for ANCA IFA and EUROPLUS Granulocyte Mosaic™ assays using EUROPattern Microscope

ANCA IFA and EUROPLUS Granulocyte Mosaic™
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 Agilent Technologies Inc. (NYSE: A) announced that the U.S. Food and Drug Administration (FDA) has approved its Dako PD-L1 IHC 22C3 pharmDx assay for expanded use in urothelial carcinoma. 

Dako PD-L1 IHC 22C3 pharmDx assay
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 FDA Approves OLUMIANT® (baricitinib) 2-mg Tablets for the Treatment of Adults with Moderately-to-Severely Active Rheumatoid Arthritis 

OLUMIANT®
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Alkermes adds Merck's Keytruda to early-stage study of ALKS 4230 in solid tumors

ALKS 4230 is an engineered fusion protein
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 Thermo Fisher Scientific Board Authorizes $2 Billion of Share Repurchases

$2 Billion Buyback